Real-world effectiveness of a widely available digital health program in adults reporting a lifetime diagnosis of ADHD.

We examined real-world evidence on whether Lumosity, a remote digital health technology designed to deliver cognitive training to healthy adults, can improve cognition and reduce inattention in adults who reported having received a prior (lifetime) diagnosis of ADHD. Over the course of Lumosity training, this cohort of commercial users was assessed repeatedly online with a neuropsychological test battery (NCPT) and a scale of attention and mood in real-world contexts (BAMS-7). More Lumosity training between successive assessments led to greater improvements on the NCPT composite measure and the attentional subscale of the BAMS-7. This positive dose-response relation was found for six of eight NCPT subtests and three of four BAMS-7 attentional items. Additional findings support the participants' clinical status and sensitivity of the assessments to ADHD symptoms. These findings provide evidence of cognitive and attentional benefits in a real-world cohort of adults reporting a lifetime diagnosis of ADHD from training with Lumosity under real-world conditions.