{"title":"网状蛋白TtRET1是嗜热四膜虫开始交配所必需的。","authors":"Sabrice Guerrier, Jordon Williams, Brandon Garcia","doi":"10.17912/micropub.biology.001763","DOIUrl":null,"url":null,"abstract":"<p><p>We recently identified <i>Tetrahymena thermophila</i> reticulon (TtRET1) as a novel marker of the endoplasmic reticulum (ER) that reveals ER morphology during the conjugation phase of mating, but its functional role was previously unknown. Here, we show that TtRET1 is required for the early initiation of mating, prior to conjugation. Furthermore, TtRET1 relocalizes during the mating reaction, suggesting it may regulate ER remodeling events necessary to initiate the mating program.</p>","PeriodicalId":74192,"journal":{"name":"microPublication biology","volume":"2025 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374191/pdf/","citationCount":"0","resultStr":"{\"title\":\"The reticulon protein, TtRET1, is required for the initiation of mating in <i>Tetrahymena thermophila</i>.\",\"authors\":\"Sabrice Guerrier, Jordon Williams, Brandon Garcia\",\"doi\":\"10.17912/micropub.biology.001763\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We recently identified <i>Tetrahymena thermophila</i> reticulon (TtRET1) as a novel marker of the endoplasmic reticulum (ER) that reveals ER morphology during the conjugation phase of mating, but its functional role was previously unknown. Here, we show that TtRET1 is required for the early initiation of mating, prior to conjugation. Furthermore, TtRET1 relocalizes during the mating reaction, suggesting it may regulate ER remodeling events necessary to initiate the mating program.</p>\",\"PeriodicalId\":74192,\"journal\":{\"name\":\"microPublication biology\",\"volume\":\"2025 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374191/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"microPublication biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17912/micropub.biology.001763\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"microPublication biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17912/micropub.biology.001763","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
The reticulon protein, TtRET1, is required for the initiation of mating in Tetrahymena thermophila.
We recently identified Tetrahymena thermophila reticulon (TtRET1) as a novel marker of the endoplasmic reticulum (ER) that reveals ER morphology during the conjugation phase of mating, but its functional role was previously unknown. Here, we show that TtRET1 is required for the early initiation of mating, prior to conjugation. Furthermore, TtRET1 relocalizes during the mating reaction, suggesting it may regulate ER remodeling events necessary to initiate the mating program.
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