Chorion Membrane and Concentrated Growth Factor Membrane in Treating Bilateral Miller's Class I and II Gingival Recessions in Maxillary Premolars - a Clinical Study.

Background: Periodontitis causes many clinical presentations, one of which is gingival recession, which leads to root exposure, hypersensitivity and esthetic issues. One of the most accepted surgical procedures of root coverage is the coronally advanced flap (CAF) technique. Newer regenerative modalities such as placental-derived chorion membranes and autologous concentrated growth factor (CGF) membranes have a higher capacity to heal because of the bioactive nature of these membranes. Material and method: A randomized controlled clinical trial study was carried out on 10 patients with bilateral gingival recession in maxillary premolars. They happened to receive CAF with chorion membrane on one side (Group A) and CGF membrane on the other side (Group B). Such clinical parameters as probing depth (PD), clinical attachment level (CAL), recession height (RH), recession width (RW) and width of keratinized tissue (WKT) were measured at baseline and after three months of follow-up. Paired and unpaired t-tests were undertaken through IBM SPSS 23.0. Results: In both groups, all clinical parameters improved statistically significant after the surgery (p < 0.05). Group A root coverage mean was 89 percent and Group B 82 percent. The postoperative values of PD, CAL, RH, RW and WKT did not differ statistically between the two groups (p < 0.05), but Group A had slightly superior results. Conclusions: Human chorion membrane and concentrated growth factor membrane being used with CAF lead to effective root coverage and clinical improvement, which is considered significant in Miller Class I and II gingival recessions. Both membranes are effective, but the chorion membrane might provide slightly better clinical results. Longitudinal research involving bigger samples should be done.