国家免疫规划中的蜱传脑炎(TBE)疫苗——为谁、何时、何地接种?

IF 2.1 4区 医学 Q1 PEDIATRICS
Acta Paediatrica Pub Date : 2025-08-26 DOI:10.1111/apa.70280
H H Askling, D Zavadska
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引用次数: 0

摘要

蜱传脑炎(TBE)病例的发病率有所增加。在过去十年中,在欧洲西部地区,蜱传脑炎病毒(TBEV)的假定传播地点日益扩大。在瑞典南部和挪威南部,监测报告的TBE病例发生率也有所增加。此外,气候变暖使得蜱虫在斯堪的纳维亚半岛北部的范围更大。在一些报告中,与青少年相比,学龄前儿童的TBE发病率往往较低,而年幼的儿童和青少年都可能出现严重的神经系统症状,如脑膜炎和脑炎。除了身体损伤外,在高达70%的感染病毒性脑炎病毒的儿童中还观察到长期认知和精神损伤。这些可能包括注意力缺陷、注意力下降和记忆力受损,这些都会严重影响日常生活和学业表现。芬兰、拉脱维亚和斯洛文尼亚已经将流行性腮腺炎疫苗纳入了它们的国家免疫规划(NIP)。流行性腮腺炎疫苗对1岁以上儿童安全有效,我们建议所有有流行性腮腺炎流行地区的国家将流行性腮腺炎疫苗纳入未来的国家免疫规划。这是一项具有成本效益的战略,更重要的是,这是一项对所有欧洲儿童至关重要的公平战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tick-Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme-For Whom, When and Where?

The incidence of Tick-borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick-borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance-reported TBE cases in southern Sweden and southern Norway. Additionally, the warmer climate has enabled ticks to be present to a greater extent in the northern part of Scandinavia. In several reports, pre-school children tend to have a lower TBE incidence rate compared to teenagers, whereas both younger children and teenagers may experience severe neurological symptoms such as meningitis and encephalitis. In addition to physical impairments, long-term cognitive and mental impairments have been observed in up to 70% of children with TBEV infection. These may include attention deficits, reduced concentration and impaired memory, which can significantly affect daily life and school performance. Finland, Latvia and Slovenia have already included TBE vaccines in their National Immunisation Program (NIP). TBE vaccines are safe and effective for children from the age of 1, and we propose all countries with endemic areas include TBE vaccines in their future NIP. This is a cost-effective strategy and, even more important, a pivotal equity strategy for all European children.

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来源期刊
Acta Paediatrica
Acta Paediatrica 医学-小儿科
CiteScore
6.50
自引率
5.30%
发文量
384
审稿时长
2-4 weeks
期刊介绍: Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries
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