牛磺酸在癌症和免疫代谢中的双重作用。

IF 12.6 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Trends in Endocrinology and Metabolism Pub Date : 2025-10-01 Epub Date: 2025-08-29 DOI:10.1016/j.tem.2025.08.001

Miaochun Xu, Yang Yu, Canhui Cao

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引用次数: 0

摘要

牛磺酸是一种有条件必需的氨基酸，在癌症中起着矛盾的作用，因为肿瘤和免疫细胞都依赖于它的重要功能。在这里，我们讨论了牛磺酸的新环境依赖功能，并提出了利用或抑制其代谢来调节癌症进展和免疫的治疗策略。

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The dual role of taurine in cancer and immune metabolism.

Taurine is a conditionally essential amino acid with paradoxical roles in cancer, as both tumor and immune cells rely on it for vital functions. Here, we discuss the emerging context-dependent functions of taurine and propose therapeutic strategies that leverage or inhibit its metabolism to modulate cancer progression and immunity.

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来源期刊

Trends in Endocrinology and Metabolism 医学-内分泌学与代谢

CiteScore

20.10

自引率

0.00%

发文量

审稿时长

82 days

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