Waleed Razzaq Chaudhry, Sana Altaf, Cara Mohammed, Sofia Fuerte
{"title":"妊娠获得性肺结核引起的胎儿-母体并发症:文献综述。","authors":"Waleed Razzaq Chaudhry, Sana Altaf, Cara Mohammed, Sofia Fuerte","doi":"10.4081/monaldi.2025.3126","DOIUrl":null,"url":null,"abstract":"<p><p>Tuberculosis (TB) during pregnancy can cause certain deleterious effects to both the mother and the fetus, leading to significant morbidity and mortality. The risk of TB rises significantly during pregnancy due to dampening of the immune response in females and certain factors yet to be studied. Since pregnant females are ruled out of clinical trials due to their pregnancy status, not much clinical data is available on how to combat TB in them or about the clinical safety and efficacy of certain drugs. Hence, not only is it important to make pregnant females vital study participants of clinical trials, but also to enhance their knowledge regarding the disease so that they may timely access quality care. It is also important to facilitate these TB-positive pregnant females through the introduction of gender-sensitive policies that are more exclusive and allow access to quality TB control programs that provide timely care, nutritional support, and quality and supportive management.</p>","PeriodicalId":51593,"journal":{"name":"Monaldi Archives for Chest Disease","volume":" ","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fetal-maternal complications due to pregnancy-acquired tuberculosis: a narrative review of the literature.\",\"authors\":\"Waleed Razzaq Chaudhry, Sana Altaf, Cara Mohammed, Sofia Fuerte\",\"doi\":\"10.4081/monaldi.2025.3126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Tuberculosis (TB) during pregnancy can cause certain deleterious effects to both the mother and the fetus, leading to significant morbidity and mortality. The risk of TB rises significantly during pregnancy due to dampening of the immune response in females and certain factors yet to be studied. Since pregnant females are ruled out of clinical trials due to their pregnancy status, not much clinical data is available on how to combat TB in them or about the clinical safety and efficacy of certain drugs. Hence, not only is it important to make pregnant females vital study participants of clinical trials, but also to enhance their knowledge regarding the disease so that they may timely access quality care. It is also important to facilitate these TB-positive pregnant females through the introduction of gender-sensitive policies that are more exclusive and allow access to quality TB control programs that provide timely care, nutritional support, and quality and supportive management.</p>\",\"PeriodicalId\":51593,\"journal\":{\"name\":\"Monaldi Archives for Chest Disease\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Monaldi Archives for Chest Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4081/monaldi.2025.3126\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monaldi Archives for Chest Disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4081/monaldi.2025.3126","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Fetal-maternal complications due to pregnancy-acquired tuberculosis: a narrative review of the literature.
Tuberculosis (TB) during pregnancy can cause certain deleterious effects to both the mother and the fetus, leading to significant morbidity and mortality. The risk of TB rises significantly during pregnancy due to dampening of the immune response in females and certain factors yet to be studied. Since pregnant females are ruled out of clinical trials due to their pregnancy status, not much clinical data is available on how to combat TB in them or about the clinical safety and efficacy of certain drugs. Hence, not only is it important to make pregnant females vital study participants of clinical trials, but also to enhance their knowledge regarding the disease so that they may timely access quality care. It is also important to facilitate these TB-positive pregnant females through the introduction of gender-sensitive policies that are more exclusive and allow access to quality TB control programs that provide timely care, nutritional support, and quality and supportive management.