辐射防护中的线性无阈值模型——德国联邦辐射防护办公室的观点。

IF 1.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES
Maria Schnelzer, Peter Scholz-Kreisel, Simone Mörtl, Werner Rühm, Michaela Kreuzer, Bastian Breustedt, Florian Gering, Udo Gerstmann, Achim Neuhäuser, Florian Rauser, Inge Paulini
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引用次数: 0

摘要

即使低剂量的电离辐射也会增加患癌症的风险吗?如果是这样,这些低剂量的风险大小是多少?这些知识是辐射防护的核心组成部分。一般而言,辐射防护依赖于基于科学发现的线性无阈值(LNT)模型。根据LNT模型,与辐射有关的癌症风险随辐射剂量成比例地降低,这甚至适用于非常低的辐射剂量。该模型对辐射剂量与致癌风险之间的关系提供了直接而实用的描述。这些假设与最新的放射生物学和辐射流行病学研究结果一致。因此,由于其简单性,该模型用于辐射防护(例如设定剂量限值)。LNT模型为辐射防护方面的审慎决策提供了一个可信的基础。然而,它并不代表电离辐射与致癌的特定生物学机制之间关系的普遍有效的描述。本备忘录概述了德国联邦辐射防护局关于在辐射防护中使用LNT模式的立场。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The linear no-threshold model in radiation protection-the view of the German Federal Office for radiation protection.

Does ionising radiation increase the risk of cancer even at low doses? If so, what is the magnitude of risk at these low doses? This knowledge is a central component of radiation protection. In general, radiation protection relies on the linear no-threshold (LNT) model, which is based on scientific findings. According to the LNT model, the radiation-related risk of cancer decreases proportionally with radiation dose and this applies even down to very low radiation doses. The model provides a straightforward and practical description of the relationship between a radiation dose and the resulting risk of cancer. These assumptions align with the latest radiobiological and radiation epidemiological findings. Therefore, and because of its simplicity, the model is used in radiation protection (e.g. for setting dose limits). The LNT model offers a plausible basis for prudent decision- making in radiation protection. However, it does not represent a universally valid description of the relationship between ionising radiation and specific biological mechanisms of carcinogenesis. This memorandum summarises the position of the Federal Office for Radiation Protection, Germany, on the use of the LNT model in radiation protection.

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来源期刊
Journal of Radiological Protection
Journal of Radiological Protection 环境科学-公共卫生、环境卫生与职业卫生
CiteScore
2.60
自引率
26.70%
发文量
137
审稿时长
18-36 weeks
期刊介绍: Journal of Radiological Protection publishes articles on all aspects of radiological protection, including non-ionising as well as ionising radiations. Fields of interest range from research, development and theory to operational matters, education and training. The very wide spectrum of its topics includes: dosimetry, instrument development, specialized measuring techniques, epidemiology, biological effects (in vivo and in vitro) and risk and environmental impact assessments. The journal encourages publication of data and code as well as results.
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