玻璃体、视网膜和绒毛膜视网膜活检的注意事项和手术入路。

IF 2.6 2区医学 Q1 OPHTHALMOLOGY

Current Opinion in Ophthalmology Pub Date : 2025-08-25 DOI:10.1097/ICU.0000000000001163

Venkatkrish M Kasetty, Dilraj S Grewal

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引用次数: 0

摘要

综述目的：本文综述了有关玻璃体和脉络膜视网膜活检的文献，重点介绍了手术技术和方法，以优化所收集样本的诊断率。最近发现：人们正在探索各种分析玻璃体样品的新方法，如无细胞DNA分析、单参数流式细胞术和质谱分析。这些方法在诊断原发性眼内淋巴瘤方面显示出良好的前景。总结：对于治疗无效或预期无效的非典型眼内炎症病例，可能需要进行玻璃体和绒毛膜视网膜活检。彻底的鉴别诊断是很重要的，它允许外科医生为获得的样本安排和优先考虑适当的检查。由于这些样本的收集可能有限或具有挑战性，因此玻璃体视网膜外科医生通过与参与样本处理的各个实验室沟通来优化其诊断产量也至关重要。

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Considerations and surgical approach to vitreous, retinal, and chorioretinal biopsy.

Purpose of review: This review summarizes the literature regarding vitreous and chorioretinal biopsy, with a focus on surgical techniques and methods to optimize diagnostic yield for the collected samples.

Recent findings: Various novel options for analyzing vitreous samples are being explored such as cell-free DNA analysis, single parameter flow cytometry, and mass spectrometry. These methods show promise in diagnosing primary intraocular lymphoma.

Summary: Vitreous and chorioretinal biopsies may be required in atypical cases of intraocular inflammation that do not respond to treatment or do not respond as anticipated. A thorough differential diagnosis is important, allowing the surgeon to order and prioritize the appropriate testing for an obtained sample. As these samples can be limited or challenging to collect, it is also crucial that vitreoretinal surgeons optimize their diagnostic yield by communicating with various labs that are involved with sample processing.

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来源期刊

Current Opinion in Ophthalmology 医学-眼科学

CiteScore

6.80

自引率

5.40%

发文量

120

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Ophthalmology is an indispensable resource featuring key up-to-date and important advances in the field from around the world. With renowned guest editors for each section, every bimonthly issue of Current Opinion in Ophthalmology delivers a fresh insight into topics such as glaucoma, refractive surgery and corneal and external disorders. With ten sections in total, the journal provides a convenient and thorough review of the field and will be of interest to researchers, clinicians and other healthcare professionals alike.