扩展耐药伤寒沙门氏菌合并罕见的致命性噬血细胞淋巴组织细胞病1例。

IF 0.6 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Tropical Doctor Pub Date : 2025-09-01 DOI:10.1177/00494755251374493

Mahnoor Baig, Waqas Siddiqui, Sara Soomro, Rabia Shah, Mariam Rashid, Muneer Sadiq

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引用次数: 0

摘要

嗜血球性淋巴组织细胞增多症（HLH）是一种致命的高炎症性临床反应，其特征是过度炎症和组织损伤，可由感染、自身免疫和恶性肿瘤继发引发。HLH通常由病毒引起，很少由细菌感染引起，如肠沙门氏菌血清型伤寒。在巴基斯坦等低收入国家，延长耐药（XDR）的发病率不断上升，可导致许多并发症，但很少继发性高毒血症。

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Extended drug-resistant Salmonella Typhi complicated by rare fatal haemophagocytic lymphohistocytosis: A case report.

Haemophagocytic lymphohistiocytosis (HLH) is a deadly hyper-inflammatory clinical response marked by excessive inflammation and tissue damage that can be secondarily triggered by infections, autoimmune and malignancy. HLH is usually caused by viruses and rarely by bacterial infections such as Salmonella enterica serovar Typhi. Its rising incidence of extended drug-resistant (XDR) in low-income countries such as Pakistan can lead to numerous complications but rarely secondary HLH.

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来源期刊

Tropical Doctor 医学-公共卫生、环境卫生与职业卫生

CiteScore

1.20

自引率

0.00%

发文量

144

审稿时长

3 months

期刊介绍： The only journal written by and for health workers in low and middle-income countries, Tropical Doctor provides medical expertise and practical advice on how to apply current medical knowledge to the special circumstances of LMIC countries. This journal provides an ideal forum for sharing experiences and establishing best practice, aiding communication between medical professionals in different environments.