Muhammad Sheraz Hameed, Syed Rafay Hussain Zaidi, Ali Iqbal, Muhammad Ahsan, Austin Mitchell, Azka Asad Mirza, Joshiah Gordon, Rahmat Gul Omarzai
{"title":"致死性面部坏死性筋膜炎:一个病例报告强调诊断和治疗的挑战。","authors":"Muhammad Sheraz Hameed, Syed Rafay Hussain Zaidi, Ali Iqbal, Muhammad Ahsan, Austin Mitchell, Azka Asad Mirza, Joshiah Gordon, Rahmat Gul Omarzai","doi":"10.1093/omcr/omaf137","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Facial Necrotizing Fasciitis (FNF) is a rare but aggressive, life-threatening infection involving the face's subcutaneous tissues and underlying musculature. It can rapidly progress to septic shock and multi-organ failure if not promptly recognized and treated. The clinical course, including severe pain, disproportionate tenderness, and systemic signs, is often the most crucial factor in diagnosis. While computed tomography (CT) can aid in identifying early signs such as soft tissue swelling and gas formation, clinical suspicion remains paramount and should not be delayed by reliance on imaging alone. Without early intervention, FNF may lead to devastating outcomes, including disfigurement, blindness, or death.</p><p><strong>Case presentation: </strong>We present the case of a 70-year-old male who developed facial necrotizing fasciitis with rapid systemic progression. He initially presented to the emergency department with acute tenderness and swelling of the right ear. CT imaging revealed extensive edema and swelling in the subcutaneous fat of the face, scalp, and neck, most prominently involving the right external ear. Despite aggressive supportive measures-including ventilatory, cardiovascular, and renal support-the infection progressed to severe multi-organ failure, ultimately resulting in death.</p><p><strong>Conclusion: </strong>This case highlights the fulminant course and high mortality risk associated with FNF. Early recognition based on clinical evaluation, supported-but not replaced-by imaging, is essential for diagnosis. Prompt intervention with broad-spectrum antibiotics and surgical debridement offers the best chance to improve outcomes and prevent catastrophic complications such as septic shock, multi-organ failure, and death.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 8","pages":"omaf137"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365970/pdf/","citationCount":"0","resultStr":"{\"title\":\"Fatal facial necrotizing fasciitis: a case report highlighting diagnostic and therapeutic challenges.\",\"authors\":\"Muhammad Sheraz Hameed, Syed Rafay Hussain Zaidi, Ali Iqbal, Muhammad Ahsan, Austin Mitchell, Azka Asad Mirza, Joshiah Gordon, Rahmat Gul Omarzai\",\"doi\":\"10.1093/omcr/omaf137\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Facial Necrotizing Fasciitis (FNF) is a rare but aggressive, life-threatening infection involving the face's subcutaneous tissues and underlying musculature. It can rapidly progress to septic shock and multi-organ failure if not promptly recognized and treated. The clinical course, including severe pain, disproportionate tenderness, and systemic signs, is often the most crucial factor in diagnosis. While computed tomography (CT) can aid in identifying early signs such as soft tissue swelling and gas formation, clinical suspicion remains paramount and should not be delayed by reliance on imaging alone. Without early intervention, FNF may lead to devastating outcomes, including disfigurement, blindness, or death.</p><p><strong>Case presentation: </strong>We present the case of a 70-year-old male who developed facial necrotizing fasciitis with rapid systemic progression. He initially presented to the emergency department with acute tenderness and swelling of the right ear. CT imaging revealed extensive edema and swelling in the subcutaneous fat of the face, scalp, and neck, most prominently involving the right external ear. Despite aggressive supportive measures-including ventilatory, cardiovascular, and renal support-the infection progressed to severe multi-organ failure, ultimately resulting in death.</p><p><strong>Conclusion: </strong>This case highlights the fulminant course and high mortality risk associated with FNF. Early recognition based on clinical evaluation, supported-but not replaced-by imaging, is essential for diagnosis. Prompt intervention with broad-spectrum antibiotics and surgical debridement offers the best chance to improve outcomes and prevent catastrophic complications such as septic shock, multi-organ failure, and death.</p>\",\"PeriodicalId\":45318,\"journal\":{\"name\":\"Oxford Medical Case Reports\",\"volume\":\"2025 8\",\"pages\":\"omaf137\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365970/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/omcr/omaf137\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omaf137","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Fatal facial necrotizing fasciitis: a case report highlighting diagnostic and therapeutic challenges.
Background: Facial Necrotizing Fasciitis (FNF) is a rare but aggressive, life-threatening infection involving the face's subcutaneous tissues and underlying musculature. It can rapidly progress to septic shock and multi-organ failure if not promptly recognized and treated. The clinical course, including severe pain, disproportionate tenderness, and systemic signs, is often the most crucial factor in diagnosis. While computed tomography (CT) can aid in identifying early signs such as soft tissue swelling and gas formation, clinical suspicion remains paramount and should not be delayed by reliance on imaging alone. Without early intervention, FNF may lead to devastating outcomes, including disfigurement, blindness, or death.
Case presentation: We present the case of a 70-year-old male who developed facial necrotizing fasciitis with rapid systemic progression. He initially presented to the emergency department with acute tenderness and swelling of the right ear. CT imaging revealed extensive edema and swelling in the subcutaneous fat of the face, scalp, and neck, most prominently involving the right external ear. Despite aggressive supportive measures-including ventilatory, cardiovascular, and renal support-the infection progressed to severe multi-organ failure, ultimately resulting in death.
Conclusion: This case highlights the fulminant course and high mortality risk associated with FNF. Early recognition based on clinical evaluation, supported-but not replaced-by imaging, is essential for diagnosis. Prompt intervention with broad-spectrum antibiotics and surgical debridement offers the best chance to improve outcomes and prevent catastrophic complications such as septic shock, multi-organ failure, and death.
期刊介绍:
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.