{"title":"胰腺癌致副瘤性肌炎横纹肌溶解1例。","authors":"Ariel Ahl, Rafi Orphali, Kumar Desai","doi":"10.1093/omcr/omaf141","DOIUrl":null,"url":null,"abstract":"<p><p>Rhabdomyolysis is a clinical syndrome characterized by the breakdown of skeletal muscle tissue, leading to the release of myoglobin and creatine kinase (CK) into the bloodstream. The condition clinically presents with myalgia, weakness, and dark urine. It can lead to kidney failure and can be life threatening. Various factors and conditions, including trauma, prolonged immobilization, strenuous exercise, infections, alcohol consumption, medications, and malignancies are potential causes. A rare cause of pancreatic cancer-induced paraneoplastic myositis has been observed. Herein, we present the case of an 87-year-old man who presented with fatigue, weight loss, and invasive pancreatic adenocarcinoma resulting in rhabdomyolysis due to paraneoplastic myositis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 8","pages":"omaf141"},"PeriodicalIF":0.4000,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365977/pdf/","citationCount":"0","resultStr":"{\"title\":\"A case of paraneoplastic myositis induced rhabdomyolysis due to pancreatic adenocarcinoma.\",\"authors\":\"Ariel Ahl, Rafi Orphali, Kumar Desai\",\"doi\":\"10.1093/omcr/omaf141\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rhabdomyolysis is a clinical syndrome characterized by the breakdown of skeletal muscle tissue, leading to the release of myoglobin and creatine kinase (CK) into the bloodstream. The condition clinically presents with myalgia, weakness, and dark urine. It can lead to kidney failure and can be life threatening. Various factors and conditions, including trauma, prolonged immobilization, strenuous exercise, infections, alcohol consumption, medications, and malignancies are potential causes. A rare cause of pancreatic cancer-induced paraneoplastic myositis has been observed. Herein, we present the case of an 87-year-old man who presented with fatigue, weight loss, and invasive pancreatic adenocarcinoma resulting in rhabdomyolysis due to paraneoplastic myositis.</p>\",\"PeriodicalId\":45318,\"journal\":{\"name\":\"Oxford Medical Case Reports\",\"volume\":\"2025 8\",\"pages\":\"omaf141\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365977/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/omcr/omaf141\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omaf141","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A case of paraneoplastic myositis induced rhabdomyolysis due to pancreatic adenocarcinoma.
Rhabdomyolysis is a clinical syndrome characterized by the breakdown of skeletal muscle tissue, leading to the release of myoglobin and creatine kinase (CK) into the bloodstream. The condition clinically presents with myalgia, weakness, and dark urine. It can lead to kidney failure and can be life threatening. Various factors and conditions, including trauma, prolonged immobilization, strenuous exercise, infections, alcohol consumption, medications, and malignancies are potential causes. A rare cause of pancreatic cancer-induced paraneoplastic myositis has been observed. Herein, we present the case of an 87-year-old man who presented with fatigue, weight loss, and invasive pancreatic adenocarcinoma resulting in rhabdomyolysis due to paraneoplastic myositis.
期刊介绍：
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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