[Epilepsy comorbid with psychiatric disorders:current status and future prospects].

The high prevalence of comorbid psychiatric disorders in epilepsy significantly impaires clinical outcomes prognosis and represents an critical phenotypic manifestation of epilepsy. In recent years, with advancements in neuroimaging, molecular genetics, and precision medicine, research on epilepsy with psychiatric comorbidities has gradually shifted from clinical phenomenology to mechanistic exploration. To date, studies on the underlying mechanisms of these comorbidities remain in their early stages. Future research directions should focus on conducting large-scale, high-quality neuroimaging, genetic, and pathological studies, as well as integrating multimodal data for comprehensive analysis. Strengthening multidisciplinary collaboration, implementing early screening, and standardizing treatment for epilepsy with psychiatric comorbidities constitute the cornerstone in improving patient outcomes.