生物可吸收胆道支架:向前迈进了一步。

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Li-Bo Zhang, Yan Wang, Xiao-Jun Yang
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引用次数: 0

摘要

Elsayed等人的病例报告提出了一种多学科方法治疗近端胆管损伤后复发性胆道狭窄。生物可吸收胆道支架是近年来治疗胆道狭窄的一种创新选择,是该方法的关键部分。与传统的金属/塑料支架不同,由聚乳酸(PLA)或聚己内酯等材料制成的生物可吸收支架在体内逐渐降解。这消除了内窥镜切除的需要,减少了患者的创伤和费用。不可降解的支架常导致并发症,如再狭窄、移位或感染。相比之下,生物可吸收支架的降解率可以根据胆管愈合过程进行调整(例如,聚乳酸支架在猪模型中保持25.7周通畅),最大限度地减少了长期并发症。我们分析了生物可吸收支架的优缺点,概述了未来的研究方向,旨在为临床实践提供有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bioresorbable biliary stents: A step forward.

The case report by Elsayed et al presented a multidisciplinary approach to treating recurrent biliary strictures following proximal bile duct injury. Bioresorbable biliary stents, an innovative option for managing biliary strictures in recent years, are a key part of this approach. Unlike traditional metal/plastic stents, bioresorbable stents made from materials like polylactic acid (PLA) or polycaprolactone gradually degrade in the body. This eliminates the need for endoscopic removal, reducing patient trauma and costs. Nondegradable stents often lead to complications such as restenosis, migration, or infection. In contrast, bioresorbable stents can have their degradation rate tailored to the bile duct healing process (e.g., PLA stents remained unobstructed for 25.7 weeks in a porcine model), minimizing long-term complications. We analyzed the advantages and disadvantages of bioresorbable stents, outlined future research directions, and aimed to offer valuable insights for clinical practice.

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来源期刊
World Journal of Clinical Cases
World Journal of Clinical Cases Medicine-General Medicine
自引率
0.00%
发文量
3384
期刊介绍: The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.
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