A I Kryukov, A V Gurov, D S Cherkasov, M A Magomedov, A A Lapchenko, Y A Raji, E O Yarushina
{"title":"【多价噬菌体复合治疗院内鼻窦炎的临床疗效观察】。","authors":"A I Kryukov, A V Gurov, D S Cherkasov, M A Magomedov, A A Lapchenko, Y A Raji, E O Yarushina","doi":"10.17116/otorino20259004133","DOIUrl":null,"url":null,"abstract":"<p><p>The article presents the results of the study of polyvalent pyobacteriophage in the complex therapy of nosocomial sinusitis in 30 patients of intensive care units of a multidisciplinary hospital in Moscow. The etiologic factors of nosocomial sinusitis manifestation were the following microorganisms: <i>Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Acinetobacter nosocomialis, Pseudomonas aeruginosa, Proteus mirabilis, Enterobacter aerogenes.</i> According to the results of the study it was revealed that at the empirical phage therapy the regression of the main clinical symptomatology was achieved in 90% of patients. The average number of days of this therapy before registration of clinical sanation of the maxillary sinus was 4±1.9. Microbiological sanitation of the maxillary sinuses was achieved in 46.7% of cases.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"90 4","pages":"33-38"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Clinical efficiency of polyvalent piobacteriophage in the complex treatment of nosocomial sinusitis].\",\"authors\":\"A I Kryukov, A V Gurov, D S Cherkasov, M A Magomedov, A A Lapchenko, Y A Raji, E O Yarushina\",\"doi\":\"10.17116/otorino20259004133\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The article presents the results of the study of polyvalent pyobacteriophage in the complex therapy of nosocomial sinusitis in 30 patients of intensive care units of a multidisciplinary hospital in Moscow. The etiologic factors of nosocomial sinusitis manifestation were the following microorganisms: <i>Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Acinetobacter nosocomialis, Pseudomonas aeruginosa, Proteus mirabilis, Enterobacter aerogenes.</i> According to the results of the study it was revealed that at the empirical phage therapy the regression of the main clinical symptomatology was achieved in 90% of patients. The average number of days of this therapy before registration of clinical sanation of the maxillary sinus was 4±1.9. Microbiological sanitation of the maxillary sinuses was achieved in 46.7% of cases.</p>\",\"PeriodicalId\":23575,\"journal\":{\"name\":\"Vestnik otorinolaringologii\",\"volume\":\"90 4\",\"pages\":\"33-38\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vestnik otorinolaringologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17116/otorino20259004133\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vestnik otorinolaringologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/otorino20259004133","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Clinical efficiency of polyvalent piobacteriophage in the complex treatment of nosocomial sinusitis].
The article presents the results of the study of polyvalent pyobacteriophage in the complex therapy of nosocomial sinusitis in 30 patients of intensive care units of a multidisciplinary hospital in Moscow. The etiologic factors of nosocomial sinusitis manifestation were the following microorganisms: Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, Acinetobacter nosocomialis, Pseudomonas aeruginosa, Proteus mirabilis, Enterobacter aerogenes. According to the results of the study it was revealed that at the empirical phage therapy the regression of the main clinical symptomatology was achieved in 90% of patients. The average number of days of this therapy before registration of clinical sanation of the maxillary sinus was 4±1.9. Microbiological sanitation of the maxillary sinuses was achieved in 46.7% of cases.