{"title":"急性缺氧暴露和右心室适应:健康个体的形态重塑、功能动力学和血流动力学意义。","authors":"T Wang, J Ma, Y Song","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>From previous studies, the right heart is considered less critical than the left heart in maintaining normal global hemodynamic performance. However, there is now substantial evidence underscoring the importance of comprehensive right ventricular (RV) function. Acute hypoxia is associated with an increase in pulmonary artery pressure (PAP), leading to changes in RV hemodynamics. Moreover, hypoxia may directly affect the RV. The current literature assessing the impact of acute hypoxia on RV hemodynamics remains insufficiently elucidated. This paper aims to delineate the effects of acute hypoxia exposure on the RV in healthy individuals.</p>","PeriodicalId":20235,"journal":{"name":"Physiological research","volume":"74 4","pages":"539-550"},"PeriodicalIF":2.0000,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440359/pdf/","citationCount":"0","resultStr":"{\"title\":\"Acute Hypoxic Exposure and Right Ventricular Adaptation: Morphological Remodeling, Functional Dynamics, and Hemodynamic Implications in Healthy Individuals.\",\"authors\":\"T Wang, J Ma, Y Song\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>From previous studies, the right heart is considered less critical than the left heart in maintaining normal global hemodynamic performance. However, there is now substantial evidence underscoring the importance of comprehensive right ventricular (RV) function. Acute hypoxia is associated with an increase in pulmonary artery pressure (PAP), leading to changes in RV hemodynamics. Moreover, hypoxia may directly affect the RV. The current literature assessing the impact of acute hypoxia on RV hemodynamics remains insufficiently elucidated. This paper aims to delineate the effects of acute hypoxia exposure on the RV in healthy individuals.</p>\",\"PeriodicalId\":20235,\"journal\":{\"name\":\"Physiological research\",\"volume\":\"74 4\",\"pages\":\"539-550\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440359/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiological research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiological research","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
Acute Hypoxic Exposure and Right Ventricular Adaptation: Morphological Remodeling, Functional Dynamics, and Hemodynamic Implications in Healthy Individuals.
From previous studies, the right heart is considered less critical than the left heart in maintaining normal global hemodynamic performance. However, there is now substantial evidence underscoring the importance of comprehensive right ventricular (RV) function. Acute hypoxia is associated with an increase in pulmonary artery pressure (PAP), leading to changes in RV hemodynamics. Moreover, hypoxia may directly affect the RV. The current literature assessing the impact of acute hypoxia on RV hemodynamics remains insufficiently elucidated. This paper aims to delineate the effects of acute hypoxia exposure on the RV in healthy individuals.
期刊介绍:
Physiological Research is a peer reviewed Open Access journal that publishes articles on normal and pathological physiology, biochemistry, biophysics, and pharmacology.
Authors can submit original, previously unpublished research articles, review articles, rapid or short communications.
Instructions for Authors - Respect the instructions carefully when submitting your manuscript. Submitted manuscripts or revised manuscripts that do not follow these Instructions will not be included into the peer-review process.
The articles are available in full versions as pdf files beginning with volume 40, 1991.
The journal publishes the online Ahead of Print /Pre-Press version of the articles that are searchable in Medline and can be cited.