预测儿童心脏移植术后上学时间的新指标:SAAT评分。

IF 1.4 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Brooke Cohen, Zhi Mei He, Roman Gorchs, Nhu Thao Nguyen Galván, John Goss, Abbas Rana
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引用次数: 0

摘要

学校出勤率与慢性病儿科患者生活质量的提高有关,并对儿童发育产生深远影响。尽管上学很重要,但很少有研究确定哪些儿科移植受者由于发病率而有延迟上学的风险。尽管上学很重要,但很少有研究确定哪些儿科移植受者由于发病率而有延迟上学的风险。我们使用UNOS数据库对5355名儿童心脏移植受者进行了单因素和多因素分析。受试者分为≤4岁和5-16岁两组。感兴趣的结果是在6岁≤4岁时返回学校,移植后2年内返回学校5-16年。移植后学校出勤率(SAAT分数)通过加权显著变量(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Index to Predict Time to School Attendance After Pediatric Heart Transplant: SAAT Score.

School attendance is associated with increased quality of life in chronically ill pediatric patients and has a profound impact on child development[ 1, 2, 3, 4, 5, 6, 7, 8 ]. Despite the importance of school attendance, little research has been done to identify which pediatric transplant recipients are at risk for delayed school attendance due to morbidity. We conducted univariate and multivariate analysis on 5355 pediatric heart transplant recipients using the UNOS database. Recipients were split into two age groups, ≤ 4 year and 5-16 years. The outcome of interest was returning to school at age 6 for ≤ 4 years, and within 2 years post-transplant for 5-16 years. School attendance after transplant (SAAT scores) were generated via weighting significant variables (p < 0.05) based on odds ratio. We found 20 significant factors combined across both cohorts. The most significant protective factors included having a VAD/TAH, age, and transplantation with an ABO incompatible organ. The most significant risk factors included low-medium functional status, age, and elevated total bilirubin. The indices for each age group had Area Under the Receiver Operating Curve (AUROC) indicating high predictive value, at 0.81 (≤ 4 years) and 0.72 (5-16 years). In this study, we created SAAT scores to predict time to school attendance in both infants and children with the intention of identifying patients at risk for delayed school attendance who may benefit from targeted interventions including Enhanced Recovery Programs.

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来源期刊
Pediatric Cardiology
Pediatric Cardiology 医学-小儿科
CiteScore
3.30
自引率
6.20%
发文量
258
审稿时长
12 months
期刊介绍: The editor of Pediatric Cardiology welcomes original manuscripts concerning all aspects of heart disease in infants, children, and adolescents, including embryology and anatomy, physiology and pharmacology, biochemistry, pathology, genetics, radiology, clinical aspects, investigative cardiology, electrophysiology and echocardiography, and cardiac surgery. Articles which may include original articles, review articles, letters to the editor etc., must be written in English and must be submitted solely to Pediatric Cardiology.
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