先天性单纯疱疹病毒性角膜炎伴双侧继发性青光眼1例报告及文献复习。

IF 2 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2025-09-03 DOI:10.1080/09273948.2025.2555382

Rohan Shah, Inae Jang Kim, Lewis Oh, Javaneh Abbasian, Asim V Farooq

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引用次数: 0

摘要

目的：强调新生儿眼部单纯疱疹病毒（HSV）感染的一个相对未被重视但重要的并发症。方法：对1例4周大的先天性眼部HSV感染患者进行6年随访。结果：我们描述了一例新生儿谁发展为双侧HSV角膜炎谁随后发展为双侧青光眼9个月后原发性感染。该患者最终需要进行多次角膜炎切开术和青光眼引流装置放置以达到IOP控制。结论：我们假设最初的HSV感染和相关炎症的结合破坏了小梁网并导致周围前粘连，最终减少了患者发育中的眼睛的流出。本病例是先天性眼部HSV及其并发症的一个潜在未被重视的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bilateral Secondary Glaucoma Associated with Congenital Herpes Simplex Virus Keratitis: A Case Report and Review of the Literature.

Purpose: To highlight a relatively underappreciated yet significant complication of neonatal ocular herpes simplex virus (HSV) infection.

Methods: Observational case report of a 4-week-old patient with congenital ocular HSV infection over the course of 6-year follow-up.

Results: We describe a case of a neonate who developed bilateral HSV keratitis who subsequently developed bilateral glaucoma 9 months following primary infection. This patient ultimately required multiple goniotomies and glaucoma drainage device placement to achieve IOP control.

Conclusions: We hypothesize that the combination of initial HSV infection and associated inflammation damaged the trabecular meshwork and led to peripheral anterior synechiae, ultimately reducing outflow in this patient's developing eyes. This case is an example of a potentially underappreciated manifestation of congenital ocular HSV and its complications.

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.