Gang Wang, Jingrong Zhou, Feng Lu, Lei Qiu, Liang Xu, Xiuwei Yang, Yongchang Miao
{"title":"【关注表达】下调microRNA‑183‑5p可通过使reticulocalbin‑2/Wnt/β‑catenin信号通路失活,抑制结直肠癌细胞的增殖和侵袭。","authors":"Gang Wang, Jingrong Zhou, Feng Lu, Lei Qiu, Liang Xu, Xiuwei Yang, Yongchang Miao","doi":"10.3892/mmr.2025.13659","DOIUrl":null,"url":null,"abstract":"<p><p>Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the Transwell assay experiments shown in Figs. 3 and 4, the 'Invasion/NC' panel in Fig. 3H appeared to contain an overlapping section of data with both the 'Invasion/NC' 'and the 'Invasion/'miR‑183‑5p mimic+RCN2 siRNA' panels in Fig. 4C, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original sources. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 19: 4475‑4483, 2019; DOI: 10.3892/mmr.2019.10059].</p>","PeriodicalId":18818,"journal":{"name":"Molecular medicine reports","volume":"32 5","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400010/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Expression of Concern] Downregulation of microRNA‑183‑5p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin‑2/Wnt/β‑catenin signaling pathway.\",\"authors\":\"Gang Wang, Jingrong Zhou, Feng Lu, Lei Qiu, Liang Xu, Xiuwei Yang, Yongchang Miao\",\"doi\":\"10.3892/mmr.2025.13659\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the Transwell assay experiments shown in Figs. 3 and 4, the 'Invasion/NC' panel in Fig. 3H appeared to contain an overlapping section of data with both the 'Invasion/NC' 'and the 'Invasion/'miR‑183‑5p mimic+RCN2 siRNA' panels in Fig. 4C, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original sources. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 19: 4475‑4483, 2019; DOI: 10.3892/mmr.2019.10059].</p>\",\"PeriodicalId\":18818,\"journal\":{\"name\":\"Molecular medicine reports\",\"volume\":\"32 5\",\"pages\":\"\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400010/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular medicine reports\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3892/mmr.2025.13659\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular medicine reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3892/mmr.2025.13659","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/24 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
[Expression of Concern] Downregulation of microRNA‑183‑5p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin‑2/Wnt/β‑catenin signaling pathway.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the Transwell assay experiments shown in Figs. 3 and 4, the 'Invasion/NC' panel in Fig. 3H appeared to contain an overlapping section of data with both the 'Invasion/NC' 'and the 'Invasion/'miR‑183‑5p mimic+RCN2 siRNA' panels in Fig. 4C, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original sources. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further. [Molecular Medicine Reports 19: 4475‑4483, 2019; DOI: 10.3892/mmr.2019.10059].
期刊介绍:
Molecular Medicine Reports is a monthly, peer-reviewed journal available in print and online, that includes studies devoted to molecular medicine, underscoring aspects including pharmacology, pathology, genetics, neurosciences, infectious diseases, molecular cardiology and molecular surgery. In vitro and in vivo studies of experimental model systems pertaining to the mechanisms of a variety of diseases offer researchers the necessary tools and knowledge with which to aid the diagnosis and treatment of human diseases.