[减少或不减少阿片类药物——这是一个问题]。

Lakartidningen Pub Date : 2025-08-20
Emmanuel Bäckryd, Paulin Andréll, Marcelo Rivano Fischer, Cecilia Grinsvall, Anders Håkansson, Thomas F Kallman, Patrik Midlöv, Åsa Ringqvist, Henrik Grelz
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引用次数: 0

摘要

缺乏长期阿片类药物治疗慢性非癌性疼痛的证据。根据欧洲指南,阿片类药物不应用于原发性慢性疼痛。重要的是不断评估每种阿片类药物治疗的益处和危害,如果有迹象,应尽早停止治疗,以防止出现不良反应。长期阿片类药物治疗是临床复杂的情况,应考虑减量(开处方)的问题。减量是一种医疗干预,需要有计划的支持和密切的后续行动。潜在的好处包括增加安全性,逆转副作用,改善整体情况。风险包括急性和长期戒断症状(包括疼痛恶化)和精神健康受损。阿片类药物的问题使用(包括阿片类药物使用障碍)发生在这一人群中,但开处方者应避免刻板印象和污名化的态度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[To taper or not to taper opioids - that is the question].

There is a lack of evidence for long-term opioid treatment of chronic non-cancer pain. According to European guidelines, opioids should not be used for primary chronic pains.  It is important to continuously assess the benefits and harms of each opioid treatment and, if indicated, discontinue it as early as possible to prevent an adverse trajectory. Long-term opioid treatment is a clinically complex situation in which the issue of tapering (deprescribing) should be considered. Tapering is a medical intervention that entails planned support and close follow-up. Potential benefits include increased safety, reversal of side effects, and an improved overall situation. Risks include acute and protracted withdrawal symptoms (including worsening pain) and impaired mental health. Problematic use of opioids (including opioid use disorder) occurs in this population, but prescribers should avoid a stereotypical and stigmatizing attitude.

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来源期刊
Lakartidningen
Lakartidningen Medicine-Medicine (all)
CiteScore
0.30
自引率
0.00%
发文量
134
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