Robert F Rudy, Anna G U Sawa, Sarah McBryan, Luke A Mugge, Katherine Thielen, Temesgen G Assefa, Derek P Lindsey, David W Polly, Juan S Uribe, Brian P Kelly, Jay D Turner
{"title":"多点骨盆固定和多棒远端结构对尸体标本近端连接生物力学的影响。","authors":"Robert F Rudy, Anna G U Sawa, Sarah McBryan, Luke A Mugge, Katherine Thielen, Temesgen G Assefa, Derek P Lindsey, David W Polly, Juan S Uribe, Brian P Kelly, Jay D Turner","doi":"10.3171/2025.4.SPINE25263","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Multipoint pelvic fixation with multirod constructs is increasingly used for long-segment deformity constructs to reduce rates of distal failure. However, more robust distal fixation may negatively impact proximal junction biomechanics, and this potential relationship has not been extensively studied.</p><p><strong>Methods: </strong>Standard nondestructive flexibility tests (7.5 Nm) were performed on 7 cadaveric specimens (L1-pelvis) to assess intervertebral flexibility (range of motion [ROM]), rod strain, and screw bending moments along a posterior fusion construct (pedicle screw and rod [PSR]) spanning L2-S1, supplemented by bilateral primary S2 alar-iliac (S2AI) fixation (2 S2AI screws and 2 rods), followed by additional S2AI screw placement and bilateral accessory rod placement spanning L4-S2AI (4 S2AI screws and 4 rods). Four conditions were tested for each specimen: 1) intact; 2) L2-S1 PSR; 3) L2-S2AI PSR; and 4) L2-S2AI plus L4-S2AI. Data were analyzed using repeated-measures ANOVA.</p><p><strong>Results: </strong>Seven cadaveric specimens were included. Proximal rod strain at the L2-3 level did not change across the varying test conditions in the 7 specimens tested (p > 0.05 for all conditions). There was no significant difference detected in proximal screw strain across conditions (p > 0.05). Finally, no significant difference was found in L2-3 ROM (p > 0.05) across instrumented variations, all of which were more rigid than intact specimens.</p><p><strong>Conclusions: </strong>Pelvic fixation with 2 or 4 screws and 2 or 4 rods, respectively, did not significantly alter proximal junction screw or rod strain in a cadaveric model. Robust pelvic fixation might protect against distal failure without deleterious effects on the proximal junction.</p>","PeriodicalId":16562,"journal":{"name":"Journal of neurosurgery. Spine","volume":" ","pages":"1-7"},"PeriodicalIF":3.1000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of multipoint pelvic fixation and multirod distal constructs on proximal junction biomechanics in cadaveric specimens.\",\"authors\":\"Robert F Rudy, Anna G U Sawa, Sarah McBryan, Luke A Mugge, Katherine Thielen, Temesgen G Assefa, Derek P Lindsey, David W Polly, Juan S Uribe, Brian P Kelly, Jay D Turner\",\"doi\":\"10.3171/2025.4.SPINE25263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Multipoint pelvic fixation with multirod constructs is increasingly used for long-segment deformity constructs to reduce rates of distal failure. However, more robust distal fixation may negatively impact proximal junction biomechanics, and this potential relationship has not been extensively studied.</p><p><strong>Methods: </strong>Standard nondestructive flexibility tests (7.5 Nm) were performed on 7 cadaveric specimens (L1-pelvis) to assess intervertebral flexibility (range of motion [ROM]), rod strain, and screw bending moments along a posterior fusion construct (pedicle screw and rod [PSR]) spanning L2-S1, supplemented by bilateral primary S2 alar-iliac (S2AI) fixation (2 S2AI screws and 2 rods), followed by additional S2AI screw placement and bilateral accessory rod placement spanning L4-S2AI (4 S2AI screws and 4 rods). Four conditions were tested for each specimen: 1) intact; 2) L2-S1 PSR; 3) L2-S2AI PSR; and 4) L2-S2AI plus L4-S2AI. Data were analyzed using repeated-measures ANOVA.</p><p><strong>Results: </strong>Seven cadaveric specimens were included. Proximal rod strain at the L2-3 level did not change across the varying test conditions in the 7 specimens tested (p > 0.05 for all conditions). There was no significant difference detected in proximal screw strain across conditions (p > 0.05). Finally, no significant difference was found in L2-3 ROM (p > 0.05) across instrumented variations, all of which were more rigid than intact specimens.</p><p><strong>Conclusions: </strong>Pelvic fixation with 2 or 4 screws and 2 or 4 rods, respectively, did not significantly alter proximal junction screw or rod strain in a cadaveric model. Robust pelvic fixation might protect against distal failure without deleterious effects on the proximal junction.</p>\",\"PeriodicalId\":16562,\"journal\":{\"name\":\"Journal of neurosurgery. Spine\",\"volume\":\" \",\"pages\":\"1-7\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of neurosurgery. Spine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3171/2025.4.SPINE25263\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neurosurgery. Spine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3171/2025.4.SPINE25263","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Impact of multipoint pelvic fixation and multirod distal constructs on proximal junction biomechanics in cadaveric specimens.
Objective: Multipoint pelvic fixation with multirod constructs is increasingly used for long-segment deformity constructs to reduce rates of distal failure. However, more robust distal fixation may negatively impact proximal junction biomechanics, and this potential relationship has not been extensively studied.
Methods: Standard nondestructive flexibility tests (7.5 Nm) were performed on 7 cadaveric specimens (L1-pelvis) to assess intervertebral flexibility (range of motion [ROM]), rod strain, and screw bending moments along a posterior fusion construct (pedicle screw and rod [PSR]) spanning L2-S1, supplemented by bilateral primary S2 alar-iliac (S2AI) fixation (2 S2AI screws and 2 rods), followed by additional S2AI screw placement and bilateral accessory rod placement spanning L4-S2AI (4 S2AI screws and 4 rods). Four conditions were tested for each specimen: 1) intact; 2) L2-S1 PSR; 3) L2-S2AI PSR; and 4) L2-S2AI plus L4-S2AI. Data were analyzed using repeated-measures ANOVA.
Results: Seven cadaveric specimens were included. Proximal rod strain at the L2-3 level did not change across the varying test conditions in the 7 specimens tested (p > 0.05 for all conditions). There was no significant difference detected in proximal screw strain across conditions (p > 0.05). Finally, no significant difference was found in L2-3 ROM (p > 0.05) across instrumented variations, all of which were more rigid than intact specimens.
Conclusions: Pelvic fixation with 2 or 4 screws and 2 or 4 rods, respectively, did not significantly alter proximal junction screw or rod strain in a cadaveric model. Robust pelvic fixation might protect against distal failure without deleterious effects on the proximal junction.
期刊介绍:
Primarily publish original works in neurosurgery but also include studies in clinical neurophysiology, organic neurology, ophthalmology, radiology, pathology, and molecular biology.