Abdullah Almutairi, Khalid Althobaiti, Mohannad Antar, Hala Al Alem, Amna Kashgari
{"title":"近乎致命的哮喘在一个12岁的女孩导致危及生命的扁桃体突出:一个病例报告。","authors":"Abdullah Almutairi, Khalid Althobaiti, Mohannad Antar, Hala Al Alem, Amna Kashgari","doi":"10.1186/s13256-025-05507-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Severe asthma exacerbations can lead to rare and life-threatening complications such as cerebral edema and tonsillar herniation. This case highlights the importance of early recognition, aggressive treatment, and the implementation of standardized pediatric intensive care unit protocols for managing critical asthma complications.</p><p><strong>Case presentation: </strong>We report the case of a 12-year-old girl of Middle Eastern descent from Saudi Arabia with a history of bronchial asthma and allergic rhinitis who developed cerebral edema and resultant tonsillar herniation following a severe asthma exacerbation. Her presentation was marked by respiratory distress unresponsive to initial therapy. Intensive management in the pediatric intensive care unit including mechanical ventilation and neuroprotective measures resulted in full neurological recovery prior to discharge.</p><p><strong>Conclusion: </strong>This case underscores the need for prompt identification and multidisciplinary management of severe asthma complications in pediatric patients to prevent irreversible outcomes.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"435"},"PeriodicalIF":0.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400729/pdf/","citationCount":"0","resultStr":"{\"title\":\"Near-fatal asthma in a 12-year-old girl leading to life-threatening tonsillar herniation: a case report.\",\"authors\":\"Abdullah Almutairi, Khalid Althobaiti, Mohannad Antar, Hala Al Alem, Amna Kashgari\",\"doi\":\"10.1186/s13256-025-05507-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Severe asthma exacerbations can lead to rare and life-threatening complications such as cerebral edema and tonsillar herniation. This case highlights the importance of early recognition, aggressive treatment, and the implementation of standardized pediatric intensive care unit protocols for managing critical asthma complications.</p><p><strong>Case presentation: </strong>We report the case of a 12-year-old girl of Middle Eastern descent from Saudi Arabia with a history of bronchial asthma and allergic rhinitis who developed cerebral edema and resultant tonsillar herniation following a severe asthma exacerbation. Her presentation was marked by respiratory distress unresponsive to initial therapy. Intensive management in the pediatric intensive care unit including mechanical ventilation and neuroprotective measures resulted in full neurological recovery prior to discharge.</p><p><strong>Conclusion: </strong>This case underscores the need for prompt identification and multidisciplinary management of severe asthma complications in pediatric patients to prevent irreversible outcomes.</p>\",\"PeriodicalId\":16236,\"journal\":{\"name\":\"Journal of Medical Case Reports\",\"volume\":\"19 1\",\"pages\":\"435\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12400729/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13256-025-05507-5\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13256-025-05507-5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Near-fatal asthma in a 12-year-old girl leading to life-threatening tonsillar herniation: a case report.
Background: Severe asthma exacerbations can lead to rare and life-threatening complications such as cerebral edema and tonsillar herniation. This case highlights the importance of early recognition, aggressive treatment, and the implementation of standardized pediatric intensive care unit protocols for managing critical asthma complications.
Case presentation: We report the case of a 12-year-old girl of Middle Eastern descent from Saudi Arabia with a history of bronchial asthma and allergic rhinitis who developed cerebral edema and resultant tonsillar herniation following a severe asthma exacerbation. Her presentation was marked by respiratory distress unresponsive to initial therapy. Intensive management in the pediatric intensive care unit including mechanical ventilation and neuroprotective measures resulted in full neurological recovery prior to discharge.
Conclusion: This case underscores the need for prompt identification and multidisciplinary management of severe asthma complications in pediatric patients to prevent irreversible outcomes.
期刊介绍:
JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect