{"title":"老年髋部骨折患者术后及营养支持后血清IgA、IgG、IgM水平、总蛋白（TP）、白蛋白（ALB）的变化","authors":"Fangqin Jin, Qin Zhang, Jiangping Weng, Xuting Pan, Qinyan Dong, Yuping Zhao","doi":"10.5937/jomb0-55434","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effects of nutritional support combined with stratified nursing under delirium risk assessment on immune function and postoperative delirium in elderly hip fracture patients.</p><p><strong>Methods: </strong>A total of 112 elderly hip fracture patients were divided into two groups: the study group (SG), which received stratified nursing and enteral nutrition, and the control group (CG), which received routine nursing with a normal diet. Key parameters were evaluated and compared, including serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB), postoperative delirium incidence, nutritional status, recovery time, and overall patient outcomes.</p><p><strong>Results: </strong>Compared to the CG, the SG demonstrated significant improvements in immune function, with increased IgA, IgG, and IgM levels, as well as higher haemoglobin, albumin, and total protein levels. The SG also experienced shorter hospital stays, earlier postoperative mobility, reduced postoperative delirium rates (1.79% vs. 14.29%), lower anxiety and depression scores, better sleep quality, and lower pain scores. Additionally, nursing satisfaction was significantly higher in the SG.</p><p><strong>Conclusions: </strong>Nutritional support combined with stratified nursing under delirium risk assessment effectively enhances immune function, reduces postoperative delirium, and accelerates recovery in elderly hip fracture patients. This approach may serve as a valuable strategy in postoperative management to improve patient outcomes.</p>","PeriodicalId":16175,"journal":{"name":"Journal of Medical Biochemistry","volume":"44 4","pages":"822-830"},"PeriodicalIF":1.5000,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363346/pdf/","citationCount":"0","resultStr":"{\"title\":\"Serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB) changes in elderly hip fracture patients after surgery and nutritional support.\",\"authors\":\"Fangqin Jin, Qin Zhang, Jiangping Weng, Xuting Pan, Qinyan Dong, Yuping Zhao\",\"doi\":\"10.5937/jomb0-55434\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This study aimed to evaluate the effects of nutritional support combined with stratified nursing under delirium risk assessment on immune function and postoperative delirium in elderly hip fracture patients.</p><p><strong>Methods: </strong>A total of 112 elderly hip fracture patients were divided into two groups: the study group (SG), which received stratified nursing and enteral nutrition, and the control group (CG), which received routine nursing with a normal diet. Key parameters were evaluated and compared, including serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB), postoperative delirium incidence, nutritional status, recovery time, and overall patient outcomes.</p><p><strong>Results: </strong>Compared to the CG, the SG demonstrated significant improvements in immune function, with increased IgA, IgG, and IgM levels, as well as higher haemoglobin, albumin, and total protein levels. The SG also experienced shorter hospital stays, earlier postoperative mobility, reduced postoperative delirium rates (1.79% vs. 14.29%), lower anxiety and depression scores, better sleep quality, and lower pain scores. Additionally, nursing satisfaction was significantly higher in the SG.</p><p><strong>Conclusions: </strong>Nutritional support combined with stratified nursing under delirium risk assessment effectively enhances immune function, reduces postoperative delirium, and accelerates recovery in elderly hip fracture patients. 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引用次数: 0
摘要
背景：本研究旨在评价谵妄风险评估下营养支持联合分层护理对老年髋部骨折患者免疫功能及术后谵妄的影响。方法：将112例老年髋部骨折患者分为两组：研究组（SG）给予分层护理和肠内营养；对照组（CG）给予常规护理和正常饮食。评估和比较关键参数，包括血清IgA、IgG、IgM水平、总蛋白（TP）、白蛋白（ALB）、术后谵妄发生率、营养状况、恢复时间和患者总体预后。结果：与CG相比，SG表现出显著的免疫功能改善，IgA、IgG和IgM水平升高，血红蛋白、白蛋白和总蛋白水平升高。SG患者住院时间更短，术后活动能力更早，术后谵妄率更低（1.79% vs. 14.29%），焦虑和抑郁评分更低，睡眠质量更好，疼痛评分更低。此外，SG组的护理满意度显著高于对照组。结论：营养支持联合分层护理在谵妄风险评估下可有效提高老年髋部骨折患者的免疫功能，减少术后谵妄，促进康复。这种方法可以作为术后管理的一种有价值的策略来改善患者的预后。
Serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB) changes in elderly hip fracture patients after surgery and nutritional support.
Background: This study aimed to evaluate the effects of nutritional support combined with stratified nursing under delirium risk assessment on immune function and postoperative delirium in elderly hip fracture patients.
Methods: A total of 112 elderly hip fracture patients were divided into two groups: the study group (SG), which received stratified nursing and enteral nutrition, and the control group (CG), which received routine nursing with a normal diet. Key parameters were evaluated and compared, including serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB), postoperative delirium incidence, nutritional status, recovery time, and overall patient outcomes.
Results: Compared to the CG, the SG demonstrated significant improvements in immune function, with increased IgA, IgG, and IgM levels, as well as higher haemoglobin, albumin, and total protein levels. The SG also experienced shorter hospital stays, earlier postoperative mobility, reduced postoperative delirium rates (1.79% vs. 14.29%), lower anxiety and depression scores, better sleep quality, and lower pain scores. Additionally, nursing satisfaction was significantly higher in the SG.
Conclusions: Nutritional support combined with stratified nursing under delirium risk assessment effectively enhances immune function, reduces postoperative delirium, and accelerates recovery in elderly hip fracture patients. This approach may serve as a valuable strategy in postoperative management to improve patient outcomes.
期刊介绍：
The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly.
The Journal publishes original scientific and specialized articles on all aspects of
clinical and medical biochemistry,
molecular medicine,
clinical hematology and coagulation,
clinical immunology and autoimmunity,
clinical microbiology,
virology,
clinical genomics and molecular biology,
genetic epidemiology,
drug measurement,
evaluation of diagnostic markers,
new reagents and laboratory equipment,
reference materials and methods,
reference values,
laboratory organization,
automation,
quality control,
clinical metrology,
all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.
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