先天性房间隔畸形——其发育、胚胎学及其临床意义的综述。

IF 2.5 Q3 DEVELOPMENTAL BIOLOGY

Journal of Developmental Biology Pub Date : 2025-08-05 DOI:10.3390/jdb13030028

Rui Caetano Oliveira, Paula Martins, Maria de Fátima Martins

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引用次数: 0

摘要

心脏和心血管系统的发育过程是人类发育的基础，受到遗传因素的高度调节。这个过程需要高度规范，以防止畸形。然而，一些心脏缺陷是可以识别的，特别是用现代成像方法。房间隔缺损（asd）尤为常见。了解ASD形成的机制是开发新的治疗策略的基础。在本文中，我们探讨心脏发育和胚胎学，重点关注房间隔缺损及其临床意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The Congenital Malformation of the Interatrial Septum-A Review of Its Development and Embryology with Clinical Implications.

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The Congenital Malformation of the Interatrial Septum-A Review of Its Development and Embryology with Clinical Implications.

The development process of the heart and cardiovascular system is fundamental in human development and highly regulated by genetic factors. This process needs to be highly regulated to prevent malformations. Nevertheless, some heart defects may be identified, especially with modern imaging methodology. Atrial septal defects (ASDs) are particularly common. Understanding the mechanisms involved in ASD formation is fundamental for developing new treatment strategies. In this article, we explore cardiac development and embryology, with a focus on atrial septal defects and their clinical implications.

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来源期刊

Journal of Developmental Biology Biochemistry, Genetics and Molecular Biology-Developmental Biology

CiteScore

4.10

自引率

18.50%

发文量

审稿时长

11 weeks

期刊介绍： The Journal of Developmental Biology (ISSN 2221-3759) is an international, peer-reviewed, quick-refereeing, open access journal, which publishes reviews, research papers and communications on the development of multicellular organisms at the molecule, cell, tissue, organ and whole organism levels. Our aim is to encourage researchers to effortlessly publish their new findings or concepts rapidly in an open access medium, overseen by their peers. There is no restriction on the length of the papers; the full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. Journal of Developmental Biology focuses on: -Development mechanisms and genetics -Cell differentiation -Embryonal development -Tissue/organism growth -Metamorphosis and regeneration of the organisms. It involves many biological fields, such as Molecular biology, Genetics, Physiology, Cell biology, Anatomy, Embryology, Cancer research, Neurobiology, Immunology, Ecology, Evolutionary biology.