使用光学相干断层扫描血管造影评估绒毛膜毛细血管灌注取决于眼睛颜色和投影伪影去除。

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
Dmitrii S Maltsev, Alexey N Kulikov, Anastasiya S Vasyukovich, Yana A Kalinicheva
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引用次数: 0

摘要

目的:探讨光学相干断层血管造影(OCTA)显示的绒毛膜毛细血管灌注变化与眼部色素沉着的关系。方法:健康个体和蓝眼睛或棕色眼睛的中枢性浆液性脉络膜视网膜病变(CSCR)患者被纳入本研究。基于平均3mm OCTA扫描(有或没有投影伪影去除(PAR))对绒毛膜毛细血管流动空洞数进行分析。计算1 ~ 5000µm2之间每1000µm2所取的流道数量和总流道面积,并对蓝眼和棕眼进行比较。结果:健康个体36例,CSCR患者28例。当PAR激活时,无论是健康眼还是CSCR眼,与蓝色眼相比,棕色眼的绒毛膜毛细血管流动空洞数量(p 2)均有统计学意义上的显著增加。PAR失活后,棕色眼与蓝色眼的绒毛膜毛细血管流腔数目及总面积差异无统计学意义(p < 0.05)。CSCR眼的大流腔数目分别为316.4±141.3个和112.9±60.1个,显著高于健康眼(p < 0.05)。这种差异是由PAR的活性造成的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Choriocapillaris perfusion assessed using optical coherence tomography angiography depends on eye color and projection artifact removal.

Aim: To study variation of choriocapillaris perfusion displayed with optical coherence tomography angiography (OCTA) in dependence of the eye pigmentation.

Methods: Healthy individuals and patients with resolved central serous chorioretinopathy (CSCR) with blue or brown eyes were enrolled in this study. Analysis of choriocapillaris flow voids number was performed based on averaged 3 mm OCTA scans with and without projection artifact removal (PAR). The number and total area of flow voids taken every 1000 µm2 between 1 and 5000 µm2, was calculated and compared between blue and brown eyes.

Results: Thirty-six healthy individuals and 28 CSCR patients were included. When PAR was active, brown eyes showed a statistically significant higher number (p < 0.05) and total area (p < 0.05) of large (1000 to 5000 µm2) choriocapillaris flow voids compared to blue eyes, in both healthy and CSCR eyes. No statistically significant difference was found in either number or total area of choriocapillaris flow voids (p > 0.05) between brown and blue eyes after inactivation of PAR. The number of large flow voids in CSCR eyes was statistically significantly higher than in healthy eyes, 316.4 ± 141.3 and 112.9 ± 60.1 (p < 0.001), respectively. Similarly, this difference was also statistically significant with inactivated PAR, 180.1 ± 96.9 and 54.9 ± 36.9, respectively (p < 0.001).

Conclusion: OCTA displays more flow voids in the choriocapillaris in brown eyes than in blue. This difference results from the activity of PAR.

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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
451
期刊介绍: International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.
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