{"title":"人体测量指数与糖尿病:基于拉夫桑詹队列研究。","authors":"Fatemeh Ayoobi, Fatemeh Ranjbarhasanabadi, Parvin Khalili, Seyed Mahdi Pourtorabi, Zahra Jamali, Maryam Karimifard, Zahra Kamiab, Alireza Vakilian","doi":"10.4103/ijpvm.ijpvm_298_23","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Various investigations have evaluated the predictive ability of different anthropometric indices for type 2 diabetes mellitus (T2DM) risk and the findings were inconsistent in different populations. This study investigated the relationship between anthropometric indicators and T2DM in the Rafsanjan Cohort Study.</p><p><strong>Methods: </strong>The present cross-sectional study included 9895 adults, aged 35-70 years, among them who have completed data, were studied. We obtained the data from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in Iran (PERSIAN). Fasting blood glucose >126 and use of glucose-lowering drugs were used from cohort data as T2DM. Anthropometric indices were compared for T2DM or prediabetes odds vs. normal group. Demographic characteristics and risk factors were compared in diabetes, prediabetes, and normal groups.</p><p><strong>Results: </strong>Of 9895 participants, about 23 (n = 2283) and 35% (n = 3455) of this population had T2DM and prediabetes, respectively. After adjusting for potential confounders, for waist-to-hip ratio (WHR) (OR = 3.25, 95% CI 2.68-3.94) and waist-to-height ratio (WHtR) (OR = 2.90, 95% CI 2.40-3.49), individuals in the highest quartile had a higher probability of developing T2DM than individuals in the lowest quartile. Also, the odds ratio of T2DM increased in participants with overweight, obesity, and abnormal waist circumference (WC) by considering a cutoff point.</p><p><strong>Conclusions: </strong>According to our findings, the strongest and weakest anthropometric indexes related to T2DM were WHR and WC, respectively.</p>","PeriodicalId":14342,"journal":{"name":"International Journal of Preventive Medicine","volume":"16 ","pages":"47"},"PeriodicalIF":1.5000,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367262/pdf/","citationCount":"0","resultStr":"{\"title\":\"Anthropometric Indices and Diabetes Disease: Based on the Rafsanjan Cohort Study.\",\"authors\":\"Fatemeh Ayoobi, Fatemeh Ranjbarhasanabadi, Parvin Khalili, Seyed Mahdi Pourtorabi, Zahra Jamali, Maryam Karimifard, Zahra Kamiab, Alireza Vakilian\",\"doi\":\"10.4103/ijpvm.ijpvm_298_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Various investigations have evaluated the predictive ability of different anthropometric indices for type 2 diabetes mellitus (T2DM) risk and the findings were inconsistent in different populations. This study investigated the relationship between anthropometric indicators and T2DM in the Rafsanjan Cohort Study.</p><p><strong>Methods: </strong>The present cross-sectional study included 9895 adults, aged 35-70 years, among them who have completed data, were studied. We obtained the data from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in Iran (PERSIAN). Fasting blood glucose >126 and use of glucose-lowering drugs were used from cohort data as T2DM. Anthropometric indices were compared for T2DM or prediabetes odds vs. normal group. Demographic characteristics and risk factors were compared in diabetes, prediabetes, and normal groups.</p><p><strong>Results: </strong>Of 9895 participants, about 23 (n = 2283) and 35% (n = 3455) of this population had T2DM and prediabetes, respectively. After adjusting for potential confounders, for waist-to-hip ratio (WHR) (OR = 3.25, 95% CI 2.68-3.94) and waist-to-height ratio (WHtR) (OR = 2.90, 95% CI 2.40-3.49), individuals in the highest quartile had a higher probability of developing T2DM than individuals in the lowest quartile. 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引用次数: 0
摘要
背景:各种研究评估了不同人体测量指标对2型糖尿病(T2DM)风险的预测能力,但不同人群的结果不一致。本研究在Rafsanjan队列研究中探讨了人体测量指标与T2DM的关系。方法:本横断面研究纳入9895名成年人,年龄在35-70岁之间,其中有完整的资料。我们从Rafsanjan队列研究(RCS)获得数据,作为伊朗(波斯)前瞻性流行病学研究的一部分。空腹血糖>126和使用降糖药物从队列数据作为T2DM。比较2型糖尿病或糖尿病前期与正常组的人体测量指标。比较糖尿病、糖尿病前期和正常组的人口学特征和危险因素。结果:在9895名参与者中,约有23人(n = 2283)和35% (n = 3455)分别患有T2DM和前驱糖尿病。在调整了潜在的混杂因素后,腰臀比(WHR) (OR = 3.25, 95% CI 2.68-3.94)和腰高比(WHtR) (OR = 2.90, 95% CI 2.40-3.49),最高四分位数的个体比最低四分位数的个体患T2DM的概率更高。此外,考虑到截断点,超重、肥胖和腰围异常(WC)的参与者患T2DM的优势比增加。结论:根据我们的研究结果,与T2DM相关的最强和最弱的人体测量指标分别是WHR和WC。
Anthropometric Indices and Diabetes Disease: Based on the Rafsanjan Cohort Study.
Background: Various investigations have evaluated the predictive ability of different anthropometric indices for type 2 diabetes mellitus (T2DM) risk and the findings were inconsistent in different populations. This study investigated the relationship between anthropometric indicators and T2DM in the Rafsanjan Cohort Study.
Methods: The present cross-sectional study included 9895 adults, aged 35-70 years, among them who have completed data, were studied. We obtained the data from the Rafsanjan Cohort Study (RCS), as a part of the prospective epidemiological research studies in Iran (PERSIAN). Fasting blood glucose >126 and use of glucose-lowering drugs were used from cohort data as T2DM. Anthropometric indices were compared for T2DM or prediabetes odds vs. normal group. Demographic characteristics and risk factors were compared in diabetes, prediabetes, and normal groups.
Results: Of 9895 participants, about 23 (n = 2283) and 35% (n = 3455) of this population had T2DM and prediabetes, respectively. After adjusting for potential confounders, for waist-to-hip ratio (WHR) (OR = 3.25, 95% CI 2.68-3.94) and waist-to-height ratio (WHtR) (OR = 2.90, 95% CI 2.40-3.49), individuals in the highest quartile had a higher probability of developing T2DM than individuals in the lowest quartile. Also, the odds ratio of T2DM increased in participants with overweight, obesity, and abnormal waist circumference (WC) by considering a cutoff point.
Conclusions: According to our findings, the strongest and weakest anthropometric indexes related to T2DM were WHR and WC, respectively.
期刊介绍:
International Journal of Preventive Medicine, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Continuous print on demand compilation of issues published. The journal’s full text is available online at http://www.ijpvmjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Preventive Medicine. Articles with clinical interest and implications will be given preference.