ADHD处方:爱尔兰参加精神卫生服务的儿童和青少年的全国调查结果。

IF 3.2 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Etain Cantwell, Ivana Nelan, Sharifah Zahirah Idid, Suzanne McCarthy, David O Driscoll
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引用次数: 0

摘要

注意缺陷多动障碍(ADHD)是一种神经发育疾病,最初出现在儿童时期。虽然治疗多动症的处方趋势已经在爱尔兰的儿科人群中进行了先前的研究,但对多动症药物的标签外处方尚未进行研究。目的:我们旨在描述爱尔兰ADHD药物处方和标签外处方。方法:本横断面研究使用了截至2021年12月31日在爱尔兰接受精神卫生服务的儿童和青少年人群的样本。根据预先确定的纳入和排除标准纳入受试者;年龄在17岁或17岁以下且至少服用过一种精神药物的患者(n = 3193)。我们描述了处方ADHD兴奋剂或非兴奋剂药物的频率和人群,以及处方的目标条件或目标症状群。我们报告了每种药物的起始和维持剂量。结果:2021年12月31日,53% (n = 1687)的儿童和青少年被开了ADHD药物,男孩比女孩更多(n = 1284比n = 395)。最常见的ADHD治疗年龄是11-13岁。处方ADHD药物的最常见适应症是目标条件ADHD (n = 1661; 98.5%)。26名患者(1.5%)因目标症状接受ADHD药物治疗,最常见的是抑郁(n = 8)和行为障碍症状(n = 8)(即超说明书处方ADHD药物)。结论:在爱尔兰,有超过一半的年轻人在接受专门的心理健康服务时接受了针对多动症的药物治疗,而且几乎所有的处方都与确诊的多动症诊断有关。其他症状组很少使用说明书外用药(
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ADHD prescribing: national findings of children and adolescents attending mental health services in Ireland.

Introduction: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition, which initially presents in childhood. While prescribing trends for treating ADHD have been previously examined in Ireland's paediatric population, off-label prescribing of ADHD medication has yet to be studied.

Aim: We aimed to describe ADHD medication prescribing and off-label prescribing of ADHD medication in Ireland.

Method: This cross-sectional study used a sample drawn from the population of children and adolescents who were attending mental health services in Ireland as of 31st December 2021. Participants were included based on predefined inclusion and exclusion criteria; those who were aged 17 years or younger and had been prescribed at least one psychotropic medication (n = 3,193). We described the frequency and population of those prescribed an ADHD stimulant or non-stimulant medication and the target condition or target symptom cluster for prescription. We reported the starting and maintenance doses of each medication.

Results: Fifty-three percentage (n = 1,687) of children and adolescents were prescribed an ADHD medication on 31st December 2021, with more boys being prescribed an ADHD medication compared to girls (n = 1,284 vs n = 395). The most common age category prescribed ADHD medication was 11-13 years of age. The most common indication for prescribing ADHD medication was the target condition ADHD (n = 1,661; 98.5%).Twenty-six patients (1.5%) were prescribed ADHD medication for target symptoms, most commonly depressive (n = 8) and behavioural disturbance symptoms (n = 8) (i.e., off-label prescribing of ADHD medication).

Conclusion: More than half of young people attending specialist mental-health services in Ireland were receiving an ADHD-specific medicine, and almost all prescriptions were tied to a confirmed ADHD diagnosis. Off-label use for other symptom clusters was rare (< 2%), indicating strong adherence to licensed indications but also highlighting the importance of continued surveillance to detect emerging off-label trends and to ensure prescribing remains evidence-based and patient-centred.

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来源期刊
CiteScore
4.10
自引率
8.30%
发文量
131
审稿时长
4-8 weeks
期刊介绍: The International Journal of Clinical Pharmacy (IJCP) offers a platform for articles on research in Clinical Pharmacy, Pharmaceutical Care and related practice-oriented subjects in the pharmaceutical sciences. IJCP is a bi-monthly, international, peer-reviewed journal that publishes original research data, new ideas and discussions on pharmacotherapy and outcome research, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics, the clinical use of medicines, medical devices and laboratory tests, information on medicines and medical devices information, pharmacy services research, medication management, other clinical aspects of pharmacy. IJCP publishes original Research articles, Review articles , Short research reports, Commentaries, book reviews, and Letters to the Editor. International Journal of Clinical Pharmacy is affiliated with the European Society of Clinical Pharmacy (ESCP). ESCP promotes practice and research in Clinical Pharmacy, especially in Europe. The general aim of the society is to advance education, practice and research in Clinical Pharmacy . Until 2010 the journal was called Pharmacy World & Science.
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