Urs Pietsch, Benedick Satari, Julian Klug, Pedro David Wendel-Garcia, Martin Müller, Lea Weber, Roland Albrecht, Robert Greif, Alexander Fuchs
{"title":"创伤与非创伤患者院前气管插管前格拉斯哥昏迷评分:一项多中心回顾性观察研究","authors":"Urs Pietsch, Benedick Satari, Julian Klug, Pedro David Wendel-Garcia, Martin Müller, Lea Weber, Roland Albrecht, Robert Greif, Alexander Fuchs","doi":"10.1097/EJA.0000000000002263","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Prehospital tracheal intubation intends to provide respiratory support and protect the airway from possible pulmonary aspiration. Trauma guidelines recommend tracheal intubation in patients with a Glasgow Coma Scale (GCS) score of <9.</p><p><strong>Objectives: </strong>We hypothesised that in clinical practice, GCS scores before prehospital tracheal intubation are lower in trauma and medical patients.</p><p><strong>Design: </strong>Retrospective observational cohort study.</p><p><strong>Setting: </strong>Swiss anaesthetist-staffed helicopter emergency medical system between 07 September 2020 and 11 December 2023.</p><p><strong>Patients: </strong>Intubated trauma and nontrauma patients ≥18 years and nonintubated patients with GCS <9 admitted to three tertiary referral Swiss hospitals.</p><p><strong>Interventions: </strong>Prehospital tracheal intubation.</p><p><strong>Main outcome measures: </strong>GCS score before prehospital tracheal intubation. Association of GCS score before prehospital tracheal intubation with length of ventilator days, intensive care unit stay, hospitalisation, and 28-day survival.</p><p><strong>Results: </strong>We screened 35 021 missions, of which 401 (335 intubated vs. 66 nonintubated) met inclusion criteria. The median GCS before prehospital tracheal intubation was 4 [IQR 3 to 6] for nontrauma and 6 [3 to 8] for trauma patients. Trauma patients with burns had a GCS score of 14 [13 to 15] before prehospital tracheal intubation. In the trauma cohort, women had a median GCS score of 5 [3 to 7] compared to men with 6 [3 to 8] (P = 0.043). The GCS before prehospital tracheal intubation was associated with length of intensive care unit stay (P = 0.042) and survival (P = 0.036) but not with length of ventilation and hospital stay.</p><p><strong>Conclusions: </strong>Overall median GCS score before prehospital tracheal intubation was lower than 8. Our data suggests that the GCS score is not suitable as the sole indicator for prehospital tracheal intubation. Further randomised controlled trials should investigate more robust intubation criteria to be included in the guidelines for trauma and nontrauma patients. Finally, a patient-centred approach should be emphasised, especially in patients with burns.</p><p><strong>Trial registration: </strong>N/A.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Glasgow coma scale score before prehospital tracheal intubation in trauma vs. nontrauma patients: A multicentre retrospective observational study.\",\"authors\":\"Urs Pietsch, Benedick Satari, Julian Klug, Pedro David Wendel-Garcia, Martin Müller, Lea Weber, Roland Albrecht, Robert Greif, Alexander Fuchs\",\"doi\":\"10.1097/EJA.0000000000002263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Prehospital tracheal intubation intends to provide respiratory support and protect the airway from possible pulmonary aspiration. Trauma guidelines recommend tracheal intubation in patients with a Glasgow Coma Scale (GCS) score of <9.</p><p><strong>Objectives: </strong>We hypothesised that in clinical practice, GCS scores before prehospital tracheal intubation are lower in trauma and medical patients.</p><p><strong>Design: </strong>Retrospective observational cohort study.</p><p><strong>Setting: </strong>Swiss anaesthetist-staffed helicopter emergency medical system between 07 September 2020 and 11 December 2023.</p><p><strong>Patients: </strong>Intubated trauma and nontrauma patients ≥18 years and nonintubated patients with GCS <9 admitted to three tertiary referral Swiss hospitals.</p><p><strong>Interventions: </strong>Prehospital tracheal intubation.</p><p><strong>Main outcome measures: </strong>GCS score before prehospital tracheal intubation. Association of GCS score before prehospital tracheal intubation with length of ventilator days, intensive care unit stay, hospitalisation, and 28-day survival.</p><p><strong>Results: </strong>We screened 35 021 missions, of which 401 (335 intubated vs. 66 nonintubated) met inclusion criteria. The median GCS before prehospital tracheal intubation was 4 [IQR 3 to 6] for nontrauma and 6 [3 to 8] for trauma patients. Trauma patients with burns had a GCS score of 14 [13 to 15] before prehospital tracheal intubation. In the trauma cohort, women had a median GCS score of 5 [3 to 7] compared to men with 6 [3 to 8] (P = 0.043). The GCS before prehospital tracheal intubation was associated with length of intensive care unit stay (P = 0.042) and survival (P = 0.036) but not with length of ventilation and hospital stay.</p><p><strong>Conclusions: </strong>Overall median GCS score before prehospital tracheal intubation was lower than 8. Our data suggests that the GCS score is not suitable as the sole indicator for prehospital tracheal intubation. Further randomised controlled trials should investigate more robust intubation criteria to be included in the guidelines for trauma and nontrauma patients. Finally, a patient-centred approach should be emphasised, especially in patients with burns.</p><p><strong>Trial registration: </strong>N/A.</p>\",\"PeriodicalId\":11920,\"journal\":{\"name\":\"European Journal of Anaesthesiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":6.8000,\"publicationDate\":\"2025-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Anaesthesiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/EJA.0000000000002263\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Anaesthesiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/EJA.0000000000002263","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Glasgow coma scale score before prehospital tracheal intubation in trauma vs. nontrauma patients: A multicentre retrospective observational study.
Background: Prehospital tracheal intubation intends to provide respiratory support and protect the airway from possible pulmonary aspiration. Trauma guidelines recommend tracheal intubation in patients with a Glasgow Coma Scale (GCS) score of <9.
Objectives: We hypothesised that in clinical practice, GCS scores before prehospital tracheal intubation are lower in trauma and medical patients.
Design: Retrospective observational cohort study.
Setting: Swiss anaesthetist-staffed helicopter emergency medical system between 07 September 2020 and 11 December 2023.
Patients: Intubated trauma and nontrauma patients ≥18 years and nonintubated patients with GCS <9 admitted to three tertiary referral Swiss hospitals.
Interventions: Prehospital tracheal intubation.
Main outcome measures: GCS score before prehospital tracheal intubation. Association of GCS score before prehospital tracheal intubation with length of ventilator days, intensive care unit stay, hospitalisation, and 28-day survival.
Results: We screened 35 021 missions, of which 401 (335 intubated vs. 66 nonintubated) met inclusion criteria. The median GCS before prehospital tracheal intubation was 4 [IQR 3 to 6] for nontrauma and 6 [3 to 8] for trauma patients. Trauma patients with burns had a GCS score of 14 [13 to 15] before prehospital tracheal intubation. In the trauma cohort, women had a median GCS score of 5 [3 to 7] compared to men with 6 [3 to 8] (P = 0.043). The GCS before prehospital tracheal intubation was associated with length of intensive care unit stay (P = 0.042) and survival (P = 0.036) but not with length of ventilation and hospital stay.
Conclusions: Overall median GCS score before prehospital tracheal intubation was lower than 8. Our data suggests that the GCS score is not suitable as the sole indicator for prehospital tracheal intubation. Further randomised controlled trials should investigate more robust intubation criteria to be included in the guidelines for trauma and nontrauma patients. Finally, a patient-centred approach should be emphasised, especially in patients with burns.
期刊介绍:
The European Journal of Anaesthesiology (EJA) publishes original work of high scientific quality in the field of anaesthesiology, pain, emergency medicine and intensive care. Preference is given to experimental work or clinical observation in man, and to laboratory work of clinical relevance. The journal also publishes commissioned reviews by an authority, editorials, invited commentaries, special articles, pro and con debates, and short reports (correspondences, case reports, short reports of clinical studies).