自闭症谱系障碍的异常手势使用与运动异常无关。

IF 3.7 3区 医学 Q1 CLINICAL NEUROLOGY
Anastasia Pavlidou, Avram Tolev, Daniela Reinhold, Gerrit Steinberg, Thomas J Müller, Sebastian Walther
{"title":"自闭症谱系障碍的异常手势使用与运动异常无关。","authors":"Anastasia Pavlidou, Avram Tolev, Daniela Reinhold, Gerrit Steinberg, Thomas J Müller, Sebastian Walther","doi":"10.1007/s00406-025-02093-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong> Gesture deficits are well-documented in youth with autism spectrum disorder (ASD), yet research in adults with ASD remains limited. Understanding the nature of gesture deficits in adulthood is essential for identifying their underlying mechanisms and potential impact on communication and daily functioning. The aim of the current study examines gesture performance in adults with ASD to explore whether these deficits persist beyond childhood and how they relate to motor impairments.</p><p><strong>Methods: </strong> We included 19 patients diagnosed with ASD and 19 age-and-gender matched controls. Gesture performance accuracy was assessed in both groups using the Test of Upper Limb Apraxia (TULIA) which was subjectively rated according to the manual by an independent single rater who was blinded to the group allocations, while manual dexterity was assessed using the performance-based coin-rotation task. We further assessed motor impairments in patients using standardized well-established motor scales to examine their potential contributions to gesture accuracy.</p><p><strong>Results: </strong> Individuals with ASD exhibited significant gesture deficits compared to controls, while manual dexterity remained preserved. Tool-based gestures appeared to be the most affected. Though ASD individuals exhibited numerous motor impairments they were not associated with gesture deficits.</p><p><strong>Conclusions: </strong> Our findings suggest that gesture deficits in ASD are not driven by the presence of motor impairments. However, given the small sample size, these results should be interpreted with caution. Future studies with larger and more diverse samples are needed to further investigate the mechanisms contributing to gesture difficulties in ASD.</p>","PeriodicalId":11822,"journal":{"name":"European Archives of Psychiatry and Clinical Neuroscience","volume":" ","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Aberrant gesture use in autism spectrum disorders is unrelated to motor abnormalities.\",\"authors\":\"Anastasia Pavlidou, Avram Tolev, Daniela Reinhold, Gerrit Steinberg, Thomas J Müller, Sebastian Walther\",\"doi\":\"10.1007/s00406-025-02093-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong> Gesture deficits are well-documented in youth with autism spectrum disorder (ASD), yet research in adults with ASD remains limited. Understanding the nature of gesture deficits in adulthood is essential for identifying their underlying mechanisms and potential impact on communication and daily functioning. The aim of the current study examines gesture performance in adults with ASD to explore whether these deficits persist beyond childhood and how they relate to motor impairments.</p><p><strong>Methods: </strong> We included 19 patients diagnosed with ASD and 19 age-and-gender matched controls. Gesture performance accuracy was assessed in both groups using the Test of Upper Limb Apraxia (TULIA) which was subjectively rated according to the manual by an independent single rater who was blinded to the group allocations, while manual dexterity was assessed using the performance-based coin-rotation task. We further assessed motor impairments in patients using standardized well-established motor scales to examine their potential contributions to gesture accuracy.</p><p><strong>Results: </strong> Individuals with ASD exhibited significant gesture deficits compared to controls, while manual dexterity remained preserved. Tool-based gestures appeared to be the most affected. Though ASD individuals exhibited numerous motor impairments they were not associated with gesture deficits.</p><p><strong>Conclusions: </strong> Our findings suggest that gesture deficits in ASD are not driven by the presence of motor impairments. However, given the small sample size, these results should be interpreted with caution. Future studies with larger and more diverse samples are needed to further investigate the mechanisms contributing to gesture difficulties in ASD.</p>\",\"PeriodicalId\":11822,\"journal\":{\"name\":\"European Archives of Psychiatry and Clinical Neuroscience\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-08-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Archives of Psychiatry and Clinical Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00406-025-02093-x\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Archives of Psychiatry and Clinical Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00406-025-02093-x","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景:手势缺陷在青少年自闭症谱系障碍(ASD)中有充分的证据,但对成人自闭症谱系障碍的研究仍然有限。了解成人手势缺陷的本质对于确定其潜在机制和对沟通和日常功能的潜在影响至关重要。当前研究的目的是研究自闭症成人的手势表现,以探索这些缺陷是否会持续到童年之后,以及它们与运动障碍的关系。方法:我们纳入了19例诊断为ASD的患者和19例年龄和性别匹配的对照组。用上肢失用测试(Test of Upper Limb Apraxia, TULIA)对两组的手势表现准确性进行评估,该测试由一名独立的评分者根据手册进行主观评分,该评分者不知道组的分配情况,而用基于表现的硬币旋转任务来评估手的灵活性。我们使用标准化的运动量表进一步评估患者的运动障碍,以检查其对手势准确性的潜在贡献。结果:与对照组相比,ASD个体表现出明显的手势缺陷,而手灵巧性保持不变。基于工具的手势似乎受到的影响最大。虽然自闭症谱系障碍患者表现出许多运动障碍,但他们与手势缺陷无关。结论:我们的研究结果表明,ASD的手势缺陷不是由运动障碍的存在引起的。然而,由于样本量小,这些结果应该谨慎解释。未来的研究需要更大、更多样化的样本来进一步研究ASD中手势困难的机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aberrant gesture use in autism spectrum disorders is unrelated to motor abnormalities.

Background:  Gesture deficits are well-documented in youth with autism spectrum disorder (ASD), yet research in adults with ASD remains limited. Understanding the nature of gesture deficits in adulthood is essential for identifying their underlying mechanisms and potential impact on communication and daily functioning. The aim of the current study examines gesture performance in adults with ASD to explore whether these deficits persist beyond childhood and how they relate to motor impairments.

Methods:  We included 19 patients diagnosed with ASD and 19 age-and-gender matched controls. Gesture performance accuracy was assessed in both groups using the Test of Upper Limb Apraxia (TULIA) which was subjectively rated according to the manual by an independent single rater who was blinded to the group allocations, while manual dexterity was assessed using the performance-based coin-rotation task. We further assessed motor impairments in patients using standardized well-established motor scales to examine their potential contributions to gesture accuracy.

Results:  Individuals with ASD exhibited significant gesture deficits compared to controls, while manual dexterity remained preserved. Tool-based gestures appeared to be the most affected. Though ASD individuals exhibited numerous motor impairments they were not associated with gesture deficits.

Conclusions:  Our findings suggest that gesture deficits in ASD are not driven by the presence of motor impairments. However, given the small sample size, these results should be interpreted with caution. Future studies with larger and more diverse samples are needed to further investigate the mechanisms contributing to gesture difficulties in ASD.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
8.80
自引率
4.30%
发文量
154
审稿时长
6-12 weeks
期刊介绍: The original papers published in the European Archives of Psychiatry and Clinical Neuroscience deal with all aspects of psychiatry and related clinical neuroscience. Clinical psychiatry, psychopathology, epidemiology as well as brain imaging, neuropathological, neurophysiological, neurochemical and moleculargenetic studies of psychiatric disorders are among the topics covered. Thus both the clinician and the neuroscientist are provided with a handy source of information on important scientific developments.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信