脊髓损伤中睡眠呼吸障碍的最新进展。

IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM
Current Opinion in Pulmonary Medicine Pub Date : 2025-11-01 Epub Date: 2025-08-20 DOI:10.1097/MCP.0000000000001207
David J Berlowitz, Marnie Graco
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引用次数: 0

摘要

综述目的:睡眠呼吸障碍(SDB)是四肢瘫痪性脊髓损伤(SCI)的直接后果,在四肢瘫痪和截瘫患者中都非常普遍,并与白天功能恶化和生活质量下降有关。尽管如此,大多数脊髓损伤患者都没有得到诊断和治疗。本文综述了近5年来关于脊髓损伤中SDB的流行病学、病理生理学和后果的研究,以及目前该人群中SDB的筛查、诊断和治疗方法。最近的发现:先前的研究主要集中在四肢瘫痪患者的SDB,然而最近的研究已经确定,截瘫患者的患病率也比一般人群高得多。SDB风险筛查问卷没有帮助,因为SDB在SCI中非常普遍,单靠问卷并不能排除真阴性病例。替代治疗,如下颌推进装置,是可行和可能有效的,替代护理模式可能提高诊断率和获得治疗的机会。摘要:最近对SCI中SDB的研究已经确定了新的,新兴的主题,但是研究人员必须进行更多的合作,以实现能够在这一相对罕见的人群中产生影响的样本量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An update on sleep disordered breathing in spinal cord injury.

Purpose of review: Sleep disordered breathing (SDB) is a direct consequence of tetraplegic spinal cord injury (SCI), is highly prevalent in both tetraplegia and paraplegia, and is associated with worse daytime functioning and reduced quality of life. Despite this, most people with SCI are undiagnosed and untreated for the disorder. This narrative review summarises research from the last 5 years on the epidemiology, pathophysiology, and consequences of SDB in SCI, as well as the current approaches to screening, diagnosis, and treatment of SDB in this population.

Recent findings: Previous research predominantly focussed on SDB in tetraplegia, however recent studies have established that people with paraplegia also experience substantially higher prevalence than the general population. SDB risk screening questionnaires are not helpful because SDB in SCI is so prevalent, and questionnaires alone cannot exclude true negative cases. Alternative treatments, such as mandibular advancement devices, are feasible and likely effective, and alternative care models may improve rates of diagnosis and access to treatments.

Summary: Recent research into SDB in SCI has identified novel, emergent themes, however researchers must collaborate more to achieve sample sizes that can deliver impact in this relatively rare population.

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来源期刊
CiteScore
6.20
自引率
0.00%
发文量
109
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Pulmonary Medicine is a highly regarded journal offering insightful editorials and on-the-mark invited reviews, covering key subjects such as asthma; cystic fibrosis; infectious diseases; diseases of the pleura; and sleep and respiratory neurobiology. Published bimonthly, each issue of Current Opinion in Pulmonary Medicine introduces world renowned guest editors and internationally recognized academics within the pulmonary field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.
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