{"title":"在“前门”导航改善疾病的抗风湿药的并发症。","authors":"Ruchir Singh, Adam P Croft","doi":"10.1016/j.clinme.2025.100504","DOIUrl":null,"url":null,"abstract":"<p><p>Disease-modifying anti-rheumatic drugs (DMARDs) have revolutionised the treatment landscape in rheumatology, reducing both disease severity and the risk of systemic comorbidities. These immunomodulatory drugs have been repurposed for use in other chronic inflammatory diseases, conferring further advantages. However, DMARDs can be associated with adverse events that have implications for the management of common symptoms and conditions that present to medical services at the 'front door'.</p>","PeriodicalId":10492,"journal":{"name":"Clinical Medicine","volume":" ","pages":"100504"},"PeriodicalIF":3.9000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451160/pdf/","citationCount":"0","resultStr":"{\"title\":\"Navigating complications of disease-modifying anti-rheumatic drugs at the 'front door'.\",\"authors\":\"Ruchir Singh, Adam P Croft\",\"doi\":\"10.1016/j.clinme.2025.100504\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Disease-modifying anti-rheumatic drugs (DMARDs) have revolutionised the treatment landscape in rheumatology, reducing both disease severity and the risk of systemic comorbidities. These immunomodulatory drugs have been repurposed for use in other chronic inflammatory diseases, conferring further advantages. However, DMARDs can be associated with adverse events that have implications for the management of common symptoms and conditions that present to medical services at the 'front door'.</p>\",\"PeriodicalId\":10492,\"journal\":{\"name\":\"Clinical Medicine\",\"volume\":\" \",\"pages\":\"100504\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451160/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.clinme.2025.100504\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/8/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clinme.2025.100504","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/20 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Navigating complications of disease-modifying anti-rheumatic drugs at the 'front door'.
Disease-modifying anti-rheumatic drugs (DMARDs) have revolutionised the treatment landscape in rheumatology, reducing both disease severity and the risk of systemic comorbidities. These immunomodulatory drugs have been repurposed for use in other chronic inflammatory diseases, conferring further advantages. However, DMARDs can be associated with adverse events that have implications for the management of common symptoms and conditions that present to medical services at the 'front door'.
期刊介绍:
Clinical Medicine is aimed at practising physicians in the UK and overseas and has relevance to all those managing or working within the healthcare sector.
Available in print and online, the journal seeks to encourage high standards of medical care by promoting good clinical practice through original research, review and comment. The journal also includes a dedicated continuing medical education (CME) section in each issue. This presents the latest advances in a chosen specialty, with self-assessment questions at the end of each topic enabling CPD accreditation to be acquired.
ISSN: 1470-2118 E-ISSN: 1473-4893 Frequency: 6 issues per year