工业化的生物催化作用。

IF 1.6 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Chimia Pub Date : 2025-08-20 DOI:10.2533/chimia.2025.522

Katrin Hecht, Rebecca Buller

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引用次数: 0

摘要

生物催化利用酶，自然界的催化剂，来加强化学合成的基本步骤，从而促进更可持续和有效的过程。酶，大分子蛋白质，在所有生物体内都能精确而高效地催化反应。这些生物催化剂已经过数千年的磨炼，以适应它们在生物系统中的特定作用；然而，通过分子生物学和生物信息学的最新进展，它们可以有效地重新设计以应对新的挑战。在这篇综述中，我们介绍了从我们实验室选择的酶来源和工程实例，展示了酶过程从学术研究到瑞士工业应用的转变。

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Industrializing Biocatalysis.

Biocatalysis leverages enzymes, nature's catalysts, to enhance essential steps in chemical synthesis, thereby promoting more sustainable and efficient processes. Enzymes, macromolecular proteins, catalyze reactions with precision and efficiency in all living organisms. These biocatalysts have been honed over millenia for their specific roles within a biological system; however, they can be effectively reengineered to address novel challenges through recent advancements in molecular biology and bioinformatics. In this review, we present selected enzyme sourcing and engineering examples from our laboratory demonstrating the transition of enzymatic processes from academic research to application in Swiss industries.

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来源期刊

Chimia 化学-化学综合

CiteScore

1.60

自引率

0.00%

发文量

144

审稿时长

2 months

期刊介绍： CHIMIA, a scientific journal for chemistry in the broadest sense covers the interests of a wide and diverse readership. Contributions from all fields of chemistry and related areas are considered for publication in the form of Review Articles and Notes. A characteristic feature of CHIMIA are the thematic issues, each devoted to an area of great current significance.