基于超滑表面的抗生物污涂层。

IF 3.1 3区 生物学 Q3 CELL BIOLOGY
Alexander B Tesler, Wolfgang H Goldmann
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引用次数: 0

摘要

用有毒涂料或抗生素处理生物污垢的传统方法存在很大的局限性和挑战,包括对周围生态系统的负面影响和耐药微生物菌株的出现。抗生素在穿透生物膜的致密和保护性结构时往往被证明是无效的,这使得传统的抗菌方法效果不佳,并导致慢性感染。有毒油漆,虽然最初有效地减少微生物定植,有助于长期的环境污染和伤害非目标生物。相比之下,诸如亲氧表面、一种特殊类型的超疏水表面和注入液体的光滑表面等新技术为传统的生物膜管理技术提供了有希望的替代方案。亲氧表面通过减少水介质与固体表面的直接接触,形成物理屏障,抑制生物膜的形成,而注入液体的光滑表面通过维持保护润滑层,防止生物沉降,增强了抗生物污染的效果。这些无毒技术不仅提供了一种更可持续和有效的对抗生物膜的方法,而且还最大限度地减少了传统处理方法对环境的影响。通过利用先进材料的独特性能,我们可以提高表面的耐用性和有效性,从而改善包括医疗设备和船舶应用在内的各个领域的成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anti-Biofouling Coatings Based on Ultra-Slippery Surfaces.

Traditional treatment of biofouling with toxic paints or antibiotics has significant limitations and challenges, including negative impacts on surrounding ecosystems and the emergence of resistant microbial strains. Antibiotics often prove ineffective in penetrating the dense and protective structure of biofilms, rendering traditional antimicrobial approaches less effective and leading to chronic infections. Toxic paints, while initially effective in reducing microbial colonization, contribute to long-term environmental contamination and harm non-target organisms. In contrast, novel technologies such as aerophilic surfaces, a special type of superhydrophobic surface, and liquid-infused slippery surfaces offer promising alternatives to conventional biofilm management technologies. While aerophilic surfaces create a physical barrier that inhibits biofilm formation by reducing the direct contact of aqueous media with solid surfaces, liquid-infused slippery surfaces enhance the anti-biofouling effect by maintaining a protective lubricating layer that prevents organisms from settling. These nontoxic technologies not only provide a more sustainable and effective means of combating biofilms but also minimize the environmental impact associated with conventional treatments. By leveraging the unique properties of advanced materials, we can increase the durability and effectiveness of surfaces, leading to improved outcomes in various fields, including medical devices and marine applications.

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来源期刊
Cell Biology International
Cell Biology International 生物-细胞生物学
CiteScore
7.60
自引率
0.00%
发文量
208
审稿时长
1 months
期刊介绍: Each month, the journal publishes easy-to-assimilate, up-to-the minute reports of experimental findings by researchers using a wide range of the latest techniques. Promoting the aims of cell biologists worldwide, papers reporting on structure and function - especially where they relate to the physiology of the whole cell - are strongly encouraged. Molecular biology is welcome, as long as articles report findings that are seen in the wider context of cell biology. In covering all areas of the cell, the journal is both appealing and accessible to a broad audience. Authors whose papers do not appeal to cell biologists in general because their topic is too specialized (e.g. infectious microbes, protozoology) are recommended to send them to more relevant journals. Papers reporting whole animal studies or work more suited to a medical journal, e.g. histopathological studies or clinical immunology, are unlikely to be accepted, unless they are fully focused on some important cellular aspect. These last remarks extend particularly to papers on cancer. Unless firmly based on some deeper cellular or molecular biological principle, papers that are highly specialized in this field, with limited appeal to cell biologists at large, should be directed towards journals devoted to cancer, there being very many from which to choose.
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