接受乌斯特金单抗治疗的克罗恩病儿童患者复发性气胸：病例报告

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

Case Reports in Gastroenterology Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI:10.1159/000543991

Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón

{"title":"接受乌斯特金单抗治疗的克罗恩病儿童患者复发性气胸：病例报告","authors":"Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón","doi":"10.1159/000543991","DOIUrl":null,"url":null,"abstract":"Introduction: We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.Case presentation: A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"134-139"},"PeriodicalIF":0.6000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882160/pdf/","citationCount":"0","resultStr":"{\"title\":\"Recurrent Pneumothorax in a Pediatric Patient with Crohn's Disease Receiving Ustekinumab Treatment: Case Report.\",\"authors\":\"Marta Freixas Bermejo, Luis Riera Soler, Laura García Martínez, Oscar Segarra Cantón\",\"doi\":\"10.1159/000543991\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.Case presentation: A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.\",\"PeriodicalId\":9614,\"journal\":{\"name\":\"Case Reports in Gastroenterology\",\"volume\":\"19 1\",\"pages\":\"134-139\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882160/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000543991\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000543991","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

简介：我们报告了一例克罗恩病患者，在开始用乌斯特金单抗治疗后复发性气胸。病例介绍：一名克罗恩病患者开始静脉注射ustekinumab诱导治疗，2个月后出现左侧气胸。它有一个非典型的演变，需要手术治疗。停药后气胸完全消失。一年后，他的克罗恩病再次发作，重新开始了ustekinumab治疗，出现了新的气胸发作。结论：据我们所知，这是第一个在两次单独尝试启动ustekinumab后复发性气胸的报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Recurrent Pneumothorax in a Pediatric Patient with Crohn's Disease Receiving Ustekinumab Treatment: Case Report.

Introduction: We present the case of a patient with Crohn's disease who experienced recurrent pneumothorax after starting treatment with ustekinumab.

Case presentation: A patient with Crohn's disease started an induction regimen with intravenous ustekinumab, and 2 months later he presented a left-sided pneumothorax. It had an atypical evolution that required surgical management. The medication was withdrawn and the pneumothorax resolved completely. One year later, he had a new flare-up of Crohn's disease and ustekinumab therapy was restarted, presenting a new episode of pneumothorax.

Conclusion: To our knowledge, this is the first report of recurrent pneumothorax following two separate attempts to initiate ustekinumab.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊