源自脂肪组织的细胞疗法的演变：历史观点、当前发展趋势和未来方向。

IF 4.9 2区生物学 Q1 BIOLOGY

Biology Direct Pub Date : 2025-08-27 DOI:10.1186/s13062-025-00682-3

Silvia Gandolfi, Elise Lupon, Audrey Varin, Agnes Coste, Brigitte Sallerin, Carla Boyer, Yanis Berkane, Benoit Chaput

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引用次数: 0

摘要

在过去的几十年里，脂肪组织在再生医学领域引起了越来越多的关注，这要归功于其再生、抗炎和促血管生成特性的发现。多年来，随着脂肪组织研究的不断深入，脂肪组织转移已经从组织转移到细胞转移，再到无细胞衍生物和生物工程的应用。了解围绕脂肪组织的这场科学革命的演变不仅有助于澄清潜在的治疗产品和适应症，而且还允许我们讨论其局限性和未来的方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Evolution of cell therapies derived from adipose tissue: historical perspectives, current development trends and future directions.

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Evolution of cell therapies derived from adipose tissue: historical perspectives, current development trends and future directions.

Over the last few decades, adipose tissue has attracted increasing attention in the field of regenerative medicine, thanks to discoveries related to its regenerative, anti-inflammatory, and pro-angiogenic properties. Over the years, with the advancement of sophisticated research around adipose tissue, there has been a shift from tissue transfer to cell transfer, and then to the application of cell-free derivatives and bioengineering. Understanding the evolution of this scientific revolution around adipose tissue not only helps clarify potential therapeutic products and indications but also allows us to discuss its limitations and future directions.

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来源期刊

Biology Direct 生物-生物学

CiteScore

6.40

自引率

10.90%

发文量

审稿时长

7 months

期刊介绍： Biology Direct serves the life science research community as an open access, peer-reviewed online journal, providing authors and readers with an alternative to the traditional model of peer review. Biology Direct considers original research articles, hypotheses, comments, discovery notes and reviews in subject areas currently identified as those most conducive to the open review approach, primarily those with a significant non-experimental component.