青少年强迫症的rTMS试验的有限证据和伦理考虑。

IF 2 Q3 PSYCHIATRY

BJPsych Bulletin Pub Date : 2025-08-22 DOI:10.1192/bjb.2025.10138

Raphael J Leo, Brandon L Mariotti

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引用次数: 0

摘要

重复经颅磁刺激（rTMS）作为成人强迫症（OCD）的辅助治疗已获得监管机构批准。然而，它在青少年中的应用在很大程度上仍未经检验。这篇社论审查了有限的现有证据，重点是目标的选择，刺激深度和方法的变化。还讨论了在弱势人群中使用rTMS的伦理挑战，包括知情同意和对神经发育的未知长期影响。尽管rTMS有望治疗难治性青少年强迫症，但在考虑更广泛的临床应用之前，必须采取谨慎和严格的伦理方法。

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Limited evidence and ethical considerations in rTMS trials for adolescents with obsessive-compulsive disorder.

Repetitive transcranial magnetic stimulation (rTMS) has gained regulatory approval as an adjunctive treatment for obsessive-compulsive disorder (OCD) in adults. However, its application in adolescents remains largely untested. This editorial examines the limited evidence available, focusing on choice of target, stimulation depth and methodological variation. Ethical challenges surrounding the use of rTMS in vulnerable populations, including informed consent and the unknown long-term effects on neurodevelopment, are also discussed. Although rTMS holds promise for treatment-resistant adolescent OCD, a cautious and ethically rigorous approach is essential before wider clinical adoption can be considered.

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来源期刊

BJPsych Bulletin PSYCHIATRY-

CiteScore

4.30

自引率

3.80%

发文量

审稿时长

15 weeks

期刊介绍： BJPsych Bulletin prioritises research, opinion and informed reflection on the state of psychiatry, management of psychiatric services, and education and training in psychiatry. It provides essential reading and practical value to psychiatrists and anyone involved in the management and provision of mental healthcare.