2-氯苯甲醛与各种苯并肼衍生物芳基腙的合成、表征及晶体结构

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Acta Chimica Slovenica Pub Date : 2024-12-03 DOI:10.17344/acsi.2024.8967

Jiaxue Liu, Shi-Yu Zhang, Wei Li, Zhonglu You

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引用次数: 0

摘要

2-氯苯甲醛分别与3-三氟甲基苯并肼、3,5-二甲氧基苯并肼、4-三氟甲基苯并肼和2-溴苯并肼在甲醇中反应得到4个新的芳酰腙。通过元素分析、IR和1H NMR对合成的化合物进行了表征，并通过x射线单晶测定进一步证实了化合物的结构。化合物对大肠杆菌、铜绿假单胞菌、枯草芽孢杆菌和金黄色葡萄球菌的抑菌活性进行了测定，结果令人感兴趣。

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Synthesis, Characterization and Crystal Structures of Aroylhydrazones Derived from 2-Chlorobenzaldehyde with Various Benzohydrazides.

Reaction of 2-chlorobenzaldehyde with 3-trifluoromethylbenzohydrazide, 3,5-dimethoxybenzohydrazide, 4-trifluoromethylbenzohydrazide and 2-bromobenzohydrazide, respectively, in methanol afforded four new aroylhydrazones. The newly synthesized compounds were characterized by means of elemental analysis, IR and 1H NMR spectroscopy, and their structures were further confirmed by X-ray single crystal determination. The compounds were assayed for their antibacterial activities against E. coli, P. aeruginosa, B. subtilis, and S. aureus and show interesting results.

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来源期刊

Acta Chimica Slovenica 化学-化学综合

CiteScore

2.50

自引率

25.00%

发文量

审稿时长

1.0 months

期刊介绍： Is an international, peer-reviewed and Open Access journal. It provides a forum for the publication of original scientific research in all fields of chemistry and closely related areas. Reviews, feature, scientific and technical articles, and short communications are welcome.