{"title":"中西医结合诊断与治疗双相情感障碍混合状态：浙江省专家共识。","authors":"Fengli Sun, Dong Shen, Yong Zhou, Baoping Xing, Zhibin Ren, Zhengxin Chen, Yong Lin, Guorong Li, Zhihan Gao, Jian Xie, Yingchun Zhang, Wei Chen, Hualiang Yu, Bing Pan, Shaojia Lu, Yonghong Jiang, Haiying Jin, Liang Li, Wei Lv, Wenwu Huang, Shugui Gao, Yunfei Tan, Suhong Ye, Xiaodong Luo, Weiming Hu, Zhiyong Lan, Gangqiao Qi, Jianming Sha, Tanglong Liu, Kedeng Fu, Xujuan Li, Weidong Jin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>As a mixed state of depressive and manic syndrome, the concept of bipolar disorder has remained unclear to date. Treatment of mixed states is difficult due to clinical recognition and poor therapeutic ideas. Based on expert consensus, it is important to establish a new definition of bipolar disorder, understand the concept of its mixed state within the field of clinical psychiatry, and explore its diagnosis and treatment using Traditional Chinese Medicine and Western medicine.</p><p><strong>Methods: </strong>The Chinese Biomedical Database, China National Knowledge Infrastructure, WANFANG Database, Chinese Social Sciences Citation Index, and PubMed were used to retrieve relevant studies according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The retrieved studies were analyzed through the lens of evidence-based medicine, and the primary conclusion was obtained after quality control of 11 items listed in the Agency for Healthcare Research and Quality (AHRQ). An expert consultation, evaluation of conflict of interest, and the Appraisal of Guidelines for Research < Evaluation II (AGREE II) assessment were completed one after another. The expert consensus was established.</p><p><strong>Results: </strong>It was defined in expert consensus that bipolar disorder mixed state includes three aspects: mixed episode in ICD-10/11, mixed feature in DSM-5, and mixed unit in Tongde criteria. The syndrome and its therapeutic methods of bipolar disorder mixed state were classified and described in the Traditional Chinese Medicine approach, which was combined with Western medicine for diagnosis and therapeutics.</p><p><strong>Conclusion: </strong>The expert consensus of integrating Traditional Chinese Medicine and Western medicine for diagnosing and treating bipolar disorder with mixed states has been established, to help clinical practice.</p><p><strong>Keywords: </strong>integrative medicine, bipolar disorder, mixed state, mixed unit, Traditional Chinese Medicine, western medicine, expert consensus.</p>","PeriodicalId":7571,"journal":{"name":"Alternative therapies in health and medicine","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnosis and Treatment of Bipolar Disorder Mixed State with Integration of Traditional Chinese Medicine and Western Medicine: Expert Consensus of Zhejiang Province in China.\",\"authors\":\"Fengli Sun, Dong Shen, Yong Zhou, Baoping Xing, Zhibin Ren, Zhengxin Chen, Yong Lin, Guorong Li, Zhihan Gao, Jian Xie, Yingchun Zhang, Wei Chen, Hualiang Yu, Bing Pan, Shaojia Lu, Yonghong Jiang, Haiying Jin, Liang Li, Wei Lv, Wenwu Huang, Shugui Gao, Yunfei Tan, Suhong Ye, Xiaodong Luo, Weiming Hu, Zhiyong Lan, Gangqiao Qi, Jianming Sha, Tanglong Liu, Kedeng Fu, Xujuan Li, Weidong Jin\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>As a mixed state of depressive and manic syndrome, the concept of bipolar disorder has remained unclear to date. Treatment of mixed states is difficult due to clinical recognition and poor therapeutic ideas. Based on expert consensus, it is important to establish a new definition of bipolar disorder, understand the concept of its mixed state within the field of clinical psychiatry, and explore its diagnosis and treatment using Traditional Chinese Medicine and Western medicine.</p><p><strong>Methods: </strong>The Chinese Biomedical Database, China National Knowledge Infrastructure, WANFANG Database, Chinese Social Sciences Citation Index, and PubMed were used to retrieve relevant studies according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The retrieved studies were analyzed through the lens of evidence-based medicine, and the primary conclusion was obtained after quality control of 11 items listed in the Agency for Healthcare Research and Quality (AHRQ). An expert consultation, evaluation of conflict of interest, and the Appraisal of Guidelines for Research < Evaluation II (AGREE II) assessment were completed one after another. The expert consensus was established.</p><p><strong>Results: </strong>It was defined in expert consensus that bipolar disorder mixed state includes three aspects: mixed episode in ICD-10/11, mixed feature in DSM-5, and mixed unit in Tongde criteria. The syndrome and its therapeutic methods of bipolar disorder mixed state were classified and described in the Traditional Chinese Medicine approach, which was combined with Western medicine for diagnosis and therapeutics.</p><p><strong>Conclusion: </strong>The expert consensus of integrating Traditional Chinese Medicine and Western medicine for diagnosing and treating bipolar disorder with mixed states has been established, to help clinical practice.</p><p><strong>Keywords: </strong>integrative medicine, bipolar disorder, mixed state, mixed unit, Traditional Chinese Medicine, western medicine, expert consensus.</p>\",\"PeriodicalId\":7571,\"journal\":{\"name\":\"Alternative therapies in health and medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alternative therapies in health and medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alternative therapies in health and medicine","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
背景：双相情感障碍作为一种抑郁和躁狂综合征的混合状态，其概念至今仍不清楚。由于临床认识不清、治疗理念不完善，混合状态的治疗较为困难。在专家共识的基础上，建立双相情感障碍的新定义，理解临床精神病学领域双相情感障碍混合状态的概念，探索中西医结合的诊断和治疗方法具有重要意义。方法：采用中国生物医学数据库、中国国家知识基础设施数据库、万方数据库、中国社会科学引文索引和PubMed数据库，根据PRISMA （Preferred Reporting Items for Systematic Reviews and meta - analysis）检索相关研究。通过循证医学的视角对检索到的研究进行分析，并对美国卫生保健研究与质量局（AHRQ）列出的11个项目进行质量控制，得出初步结论。先后完成了专家咨询、利益冲突评估、研究指南评估<评估II （AGREE II）评估。专家达成共识。结果：专家共识定义双相情感障碍混合状态包括三个方面：ICD-10/11中的混合发作、DSM-5中的混合特征和同德标准中的混合单元。以中医方法对双相情感障碍混合状态的证候及其治疗方法进行分类描述，并结合西医进行诊断和治疗。结论：建立了中西医结合诊断和治疗双相情感障碍混合状态的专家共识，有助于临床实践。关键词：中西医结合，躁郁症，混合状态，混合单元，中医，西医，专家共识
Diagnosis and Treatment of Bipolar Disorder Mixed State with Integration of Traditional Chinese Medicine and Western Medicine: Expert Consensus of Zhejiang Province in China.
Background: As a mixed state of depressive and manic syndrome, the concept of bipolar disorder has remained unclear to date. Treatment of mixed states is difficult due to clinical recognition and poor therapeutic ideas. Based on expert consensus, it is important to establish a new definition of bipolar disorder, understand the concept of its mixed state within the field of clinical psychiatry, and explore its diagnosis and treatment using Traditional Chinese Medicine and Western medicine.
Methods: The Chinese Biomedical Database, China National Knowledge Infrastructure, WANFANG Database, Chinese Social Sciences Citation Index, and PubMed were used to retrieve relevant studies according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The retrieved studies were analyzed through the lens of evidence-based medicine, and the primary conclusion was obtained after quality control of 11 items listed in the Agency for Healthcare Research and Quality (AHRQ). An expert consultation, evaluation of conflict of interest, and the Appraisal of Guidelines for Research < Evaluation II (AGREE II) assessment were completed one after another. The expert consensus was established.
Results: It was defined in expert consensus that bipolar disorder mixed state includes three aspects: mixed episode in ICD-10/11, mixed feature in DSM-5, and mixed unit in Tongde criteria. The syndrome and its therapeutic methods of bipolar disorder mixed state were classified and described in the Traditional Chinese Medicine approach, which was combined with Western medicine for diagnosis and therapeutics.
Conclusion: The expert consensus of integrating Traditional Chinese Medicine and Western medicine for diagnosing and treating bipolar disorder with mixed states has been established, to help clinical practice.
Keywords: integrative medicine, bipolar disorder, mixed state, mixed unit, Traditional Chinese Medicine, western medicine, expert consensus.
期刊介绍：
Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field.
Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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