下鼻甲射频手术对鼻腔菌群影响的前瞻性研究。

IF 2.3 3区 医学 Q1 OTORHINOLARYNGOLOGY
American Journal of Rhinology & Allergy Pub Date : 2025-11-01 Epub Date: 2025-08-21 DOI:10.1177/19458924251370502
Fatma G I Bayraktar, Ragıp Ç Çelik, Güler Berkiten, Çiğdem Arabaci, Kenan Ak, Tuğçe Gültepe Zorlu, Yavuz Uyar
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引用次数: 0

摘要

背景下鼻甲肥大是慢性鼻塞的常见原因,射频治疗已成为一种有效的微创治疗选择。然而,该手术对鼻腔菌群的影响和术后抗生素的需求仍不清楚。目的探讨下鼻甲射频治疗对鼻腔菌群的影响及术后使用抗生素的必要性。方法选取2023年11月至2024年2月间因慢性鼻塞就诊于耳鼻咽喉科门诊的45例患者,年龄18 ~ 65岁。患者患有非感染性下鼻甲肥大,建议进行下鼻甲射频治疗,并同意接受手术。术前及术后1个月取鼻拭子送临床微生物科培养。比较两种拭子分离的微生物。采用SPSS 26.0软件对研究数据进行统计分析。结果射频治疗后总细菌定植数与术前比较差异无统计学意义(p = 0.44)。手术前后正常菌群元素和潜在致病菌总数无显著差异(p =。10, p = .23)。在分离的正常菌群微生物中,除凝固酶阴性葡萄球菌外,其余菌种的细菌定植数均无显著差异,其中凝固酶阴性葡萄球菌的细菌定植数显著减少(p < 0.05)。0.05, p = .004)。结论本研究数据提示下鼻甲射频治疗对鼻腔菌群定植无明显影响,未引起致病菌数量和种类的明显增加,术后无需抗生素治疗。然而,需要更大样本量的进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Inferior Turbinate Radiofrequency Procedure on Nasal Flora: A Prospective Study.

BackgroundInferior turbinate hypertrophy is a common cause of chronic nasal obstruction, and radiofrequency treatment has become an effective minimally invasive option for management. However, the impact of this procedure on nasal bacterial flora and the need for postoperative antibiotics remains unclear.ObjectiveTo investigate the effect of inferior turbinate radiofrequency treatment on the nasal cavity bacterial flora and the need for postoperative antibiotics.MethodsForty-five voluntary patients aged 18 to 65, who were referred to the Otorhinolaryngology clinic between 11/2023 and 02/2024 due to chronic nasal obstruction, were included in the study. The patients had noninfective inferior turbinate hypertrophy, were recommended for inferior turbinate radiofrequency treatment, and agreed to undergo the procedure. Before and one month after the procedure, nasal swabs were taken from the patients and sent to the Clinical Microbiology Department for culture. The microorganisms isolated from both swabs were compared. The statistical analysis of the study data was conducted using SPSS 26.0 software.ResultsNo significant difference was observed in the total bacterial colonization count after the radiofrequency procedure compared to before the procedure (p = .44). There was no significant difference in the total count of normal flora elements and potentially pathogenic bacteria between the pre and post procedure (p = .10, p = .23). Among the isolated normal flora microorganisms, no significant difference was observed in the bacterial colonization count for all species except coagulase-negative staphylococci, in which a significant decrease was detected (p > .05, p = .004).ConclusionThe data from this study suggest that inferior turbinate radiofrequency treatment does not significantly affect nasal flora bacterial colonization and does not cause a significant increase in the number and variety of pathogenic bacteria, thereby indicating that postoperative antibiotic therapy is not necessary. However, further studies with a larger sample size are required.

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来源期刊
CiteScore
5.60
自引率
11.50%
发文量
82
审稿时长
4-8 weeks
期刊介绍: The American Journal of Rhinology & Allergy is a peer-reviewed, scientific publication committed to expanding knowledge and publishing the best clinical and basic research within the fields of Rhinology & Allergy. Its focus is to publish information which contributes to improved quality of care for patients with nasal and sinus disorders. Its primary readership consists of otolaryngologists, allergists, and plastic surgeons. Published material includes peer-reviewed original research, clinical trials, and review articles.
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