先进治疗药物正在成熟：临床试验前景的管道分析。

IF 7.5 2区医学 Q1 PHARMACOLOGY & PHARMACY

Drug Discovery Today Pub Date : 2025-08-23 DOI:10.1016/j.drudis.2025.104459

Michiel Vanhaeren , Rik Gijsbers , Walter Van Dyck , Isabelle Huys , Steven Simoens

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引用次数: 0

摘要

先进治疗药物（atmp）是一类独特的基于细胞、基因或组织的生物药物。通过搜索四个数据库，该分析确定了2008年调查atmp的试验，并根据不同的特征（如发起人类型和临床开发阶段）对它们进行了描述。这一特征表明，就正在开发的产品数量、针对的疾病和正在追求的技术而言，atmp市场正在成熟。这一特征是为了帮助进一步讨论日益增长的atmp临床试验景观，并告知医疗保健支付者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advanced therapy medicinal products are coming of age: A pipeline analysis of the clinical trial landscape

Advanced therapy medicinal products (ATMPs) are a unique class of biological medicines that are based on cells, genes, or tissues. Searching four databases, this analysis identified 2008 trials that investigated ATMPs and characterised them according to various characteristics, such as the sponsor type and phase of clinical development. This characterisation revealed that the market for ATMPs is maturing in terms of the number of products in development, the diseases being targeted, and the technologies being pursued. This characterisation is meant to help further the discussion on the ever-growing clinical trial landscape of ATMPs and inform healthcare payers.

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来源期刊

Drug Discovery Today 医学-药学

CiteScore

14.80

自引率

2.70%

发文量

293

审稿时长

6 months

期刊介绍： Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.