{"title":"院前延迟对老年髋部骨折患者术后并发症和5年死亡率的影响","authors":"Yu Jiang , Shuhuai Tan , Kaihua Qin , Sizheng Steven Zhao , Tianjunke Zhou , Dingfa Liang , Tingjie Zhao , Wen Ju , Zhi Wen , Hui Guo , Yong Xie , Xiang Cui , Peifu Tang , Houchen Lyu , Licheng Zhang","doi":"10.1016/j.injury.2025.112727","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>Guidelines recommended early surgery for hip fracture to improve outcomes, yet it is often hindered by prehospital delays. However, it remains unclear whether prehospital delay independently leads to poor outcomes of the well-recognized impact of in-hospital delay for hip fracture surgery.</div></div><div><h3>Methods</h3><div>We included patients aged over 60 years old who underwent surgery for their first acute hip fracture between 2000 and 2022 at a national trauma center in Beijing, China. Patients were categorized into short prehospital delay (time from injury to hospital admission ≤ 48 h) or long prehospital delay (> 48 h) groups. The primary outcome was a composite endpoint of postoperative complications, and the secondary outcome was 5-year all-cause mortality. Multivariate logistic and Cox regression models were used to assess the association between exposure and outcomes.</div></div><div><h3>Results</h3><div>Among 3103 included patients (mean age, 78.1 ± 8.3 years; 69.1 % female), 1152 (37.1 %) experienced a long prehospital delay. Patients with long prehospital delay had a higher risk of postoperative complications (28.8 % vs. 16.8 %; adjusted odds ratio = 1.41, 95 % CI, 1.12–1.76, <em>P</em> < 0.01) and 5-year all-cause mortality (63.9 vs. 43.3 per 1000 person–years; adjusted hazard ratio = 1.25, 95 % CI, 1.01–1.57, <em>P</em> < 0.05) compared to those with short prehospital delay after adjusting for potential confounders including in-hospital delay.</div></div><div><h3>Conclusion</h3><div>Prehospital delays is associated with higher risk of postoperative complications and 5-year mortality in older adults with hip fractures, highlighting the need for public health policies to minimize such delays.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 11","pages":"Article 112727"},"PeriodicalIF":2.0000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of prehospital delay on postoperative complications and 5-year mortality in older adults with hip fractures\",\"authors\":\"Yu Jiang , Shuhuai Tan , Kaihua Qin , Sizheng Steven Zhao , Tianjunke Zhou , Dingfa Liang , Tingjie Zhao , Wen Ju , Zhi Wen , Hui Guo , Yong Xie , Xiang Cui , Peifu Tang , Houchen Lyu , Licheng Zhang\",\"doi\":\"10.1016/j.injury.2025.112727\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>Guidelines recommended early surgery for hip fracture to improve outcomes, yet it is often hindered by prehospital delays. However, it remains unclear whether prehospital delay independently leads to poor outcomes of the well-recognized impact of in-hospital delay for hip fracture surgery.</div></div><div><h3>Methods</h3><div>We included patients aged over 60 years old who underwent surgery for their first acute hip fracture between 2000 and 2022 at a national trauma center in Beijing, China. Patients were categorized into short prehospital delay (time from injury to hospital admission ≤ 48 h) or long prehospital delay (> 48 h) groups. The primary outcome was a composite endpoint of postoperative complications, and the secondary outcome was 5-year all-cause mortality. Multivariate logistic and Cox regression models were used to assess the association between exposure and outcomes.</div></div><div><h3>Results</h3><div>Among 3103 included patients (mean age, 78.1 ± 8.3 years; 69.1 % female), 1152 (37.1 %) experienced a long prehospital delay. Patients with long prehospital delay had a higher risk of postoperative complications (28.8 % vs. 16.8 %; adjusted odds ratio = 1.41, 95 % CI, 1.12–1.76, <em>P</em> < 0.01) and 5-year all-cause mortality (63.9 vs. 43.3 per 1000 person–years; adjusted hazard ratio = 1.25, 95 % CI, 1.01–1.57, <em>P</em> < 0.05) compared to those with short prehospital delay after adjusting for potential confounders including in-hospital delay.</div></div><div><h3>Conclusion</h3><div>Prehospital delays is associated with higher risk of postoperative complications and 5-year mortality in older adults with hip fractures, highlighting the need for public health policies to minimize such delays.</div></div>\",\"PeriodicalId\":54978,\"journal\":{\"name\":\"Injury-International Journal of the Care of the Injured\",\"volume\":\"56 11\",\"pages\":\"Article 112727\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-08-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Injury-International Journal of the Care of the Injured\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0020138325005856\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Injury-International Journal of the Care of the Injured","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0020138325005856","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
目的:指南推荐髋部骨折的早期手术以改善预后,然而院前延误往往阻碍了手术的进行。然而,目前尚不清楚院前延迟是否独立导致髋部骨折手术院内延迟的不良结果。方法:我们纳入了2000年至2022年间在中国北京国家创伤中心接受首次急性髋部骨折手术的60岁以上患者。将患者分为短院前延迟组(损伤至入院时间≤48 h)和长院前延迟组(> 48 h)。主要终点是术后并发症的综合终点,次要终点是5年全因死亡率。使用多变量logistic和Cox回归模型来评估暴露与结果之间的关系。结果3103例患者(平均年龄78.1±8.3岁,女性占69.1%)中,1152例(37.1%)出现较长的院前延迟。院前延迟较长的患者术后并发症风险(28.8%比16.8%;校正优势比= 1.41,95% CI, 1.12-1.76, P < 0.01)和5年全因死亡率(每1000人年63.9比43.3;校正危险比= 1.25,95% CI, 1.01-1.57, P < 0.05)高于院前延迟较短的患者,校正混杂因素包括院内延迟。结论院前延迟与老年髋部骨折患者术后并发症和5年死亡率较高相关,强调了制定公共卫生政策以尽量减少此类延迟的必要性。
Impact of prehospital delay on postoperative complications and 5-year mortality in older adults with hip fractures
Purpose
Guidelines recommended early surgery for hip fracture to improve outcomes, yet it is often hindered by prehospital delays. However, it remains unclear whether prehospital delay independently leads to poor outcomes of the well-recognized impact of in-hospital delay for hip fracture surgery.
Methods
We included patients aged over 60 years old who underwent surgery for their first acute hip fracture between 2000 and 2022 at a national trauma center in Beijing, China. Patients were categorized into short prehospital delay (time from injury to hospital admission ≤ 48 h) or long prehospital delay (> 48 h) groups. The primary outcome was a composite endpoint of postoperative complications, and the secondary outcome was 5-year all-cause mortality. Multivariate logistic and Cox regression models were used to assess the association between exposure and outcomes.
Results
Among 3103 included patients (mean age, 78.1 ± 8.3 years; 69.1 % female), 1152 (37.1 %) experienced a long prehospital delay. Patients with long prehospital delay had a higher risk of postoperative complications (28.8 % vs. 16.8 %; adjusted odds ratio = 1.41, 95 % CI, 1.12–1.76, P < 0.01) and 5-year all-cause mortality (63.9 vs. 43.3 per 1000 person–years; adjusted hazard ratio = 1.25, 95 % CI, 1.01–1.57, P < 0.05) compared to those with short prehospital delay after adjusting for potential confounders including in-hospital delay.
Conclusion
Prehospital delays is associated with higher risk of postoperative complications and 5-year mortality in older adults with hip fractures, highlighting the need for public health policies to minimize such delays.
期刊介绍:
Injury was founded in 1969 and is an international journal dealing with all aspects of trauma care and accident surgery. Our primary aim is to facilitate the exchange of ideas, techniques and information among all members of the trauma team.