应用CT灌注成像的预测护理模型可改善急性脑出血的预后

IF 2.5 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES
Hui Su , Hao Wang , Shuai Su , Yuan Liu , Zhitao Fan
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引用次数: 0

摘要

目的评价基于CT灌注成像参数的预测护理模型(CTP-PNM)与常规护理(RN)的对比效果。具体来说,我们评估了急性脑出血(ACH)患者的预后、神经恢复、生化指标、症状缓解、生活质量和并发症。方法回顾性队列研究纳入2021年5月至2023年5月期间治疗的225例ACH患者(RN组:n = 121; CTP-PNM组:n = 104)。注册护士组接受标准护理。CTP-PNM组接受RN加有针对性的干预,如加强颅内压(ICP)监测和抗炎措施,以ctp定义的个体风险为指导。比较基线特征、生化指标、症状、神经、认知、情绪、功能和生活质量量表、总体治疗效果和并发症。结果两组在基线时具有可比性。护理后,CTP-PNM组在神经功能(如NIHSS评分)、炎症指标、情绪状态和生活质量方面均有显著改善(P < 0.05)。CTP-PNM的总疗效更高(P < 0.001),总并发症发生率显著降低(P = 0.016),特别是感染、深静脉血栓形成(DVT)、压疮和胃肠道出血。结论基于CT灌注参数的预测护理模型对ACH患者的护理效果优于常规护理。它不仅能促进神经系统恢复,减少炎症标志物,缓解症状,改善情绪状态和生活质量,还能提高整体治疗效果,减少并发症。这种方法有可能为管理ACH患者制定新的标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A predictive nursing model using CT perfusion imaging improves outcomes in acute cerebral hemorrhage

Purpose

To evaluate the impact of a predictive nursing model (CTP-PNM) based on CT perfusion imaging parameters compared to routine nursing (RN). Specifically, we assessed prognosis, neurological recovery, biochemical markers, symptom relief, quality of life, and complications in patients with acute cerebral hemorrhage (ACH).

Methods

A retrospective cohort study included 225 ACH patients (RN group: n = 121; CTP-PNM group: n = 104) treated between May 2021 and May 2023. The RN group received standard care. The CTP-PNM group received RN plus targeted interventions, such as intensified intracranial pressure (ICP) monitoring and anti-inflammatory measures, guided by individual CTP-defined risks. Baseline characteristics, biochemical markers, symptoms, neurological, cognitive, emotional, functional, and quality-of-life scales, overall treatment effectiveness, and complications were compared.

Results

Groups were comparable at baseline. After nursing, the CTP-PNM group demonstrated significant improvements across neurological function (e.g., NIHSS score), inflammatory markers, emotional state, and quality of life (all P < 0.05). CTP-PNM had higher total efficacy (P < 0.001) and significantly lower total complication rates (P = 0.016), particularly infections, deep vein thrombosis (DVT), pressure sores, and Gastrointestinal (GI) hemorrhage.

Conclusion

The CT perfusion parameter-based predictive nursing model represents a significant advance over routine care for ACH patients. It not only enhances neurological recovery, reduces inflammatory markers, alleviates symptoms, improves emotional state and quality of life but also increases overall treatment effectiveness and decreases complications. This approach has the potential to set a new standard for managing ACH patients.
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来源期刊
自引率
5.90%
发文量
130
审稿时长
16 weeks
期刊介绍: Journal of Radiation Research and Applied Sciences provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and applications of nuclear, radiation and isotopes in biology, medicine, drugs, biochemistry, microbiology, agriculture, entomology, food technology, chemistry, physics, solid states, engineering, environmental and applied sciences.
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