癌细胞群中顺铂摄取的分化-如何使用单细胞ICP-MS“破解这个难题”？

IF 3.3 3区化学 Q2 CHEMISTRY, ANALYTICAL

Analyst Pub Date : 2025-09-02 DOI:10.1039/d5an00152h

Zuzanna Szymańska, Magdalena Matczuk, Agnieszka Zuchowska, Pawel Romanczuk, Andrei R. Timerbaev, Maciej Jarosz

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引用次数: 0

摘要

本文提出了一种基于单细胞电感耦合等离子体质谱法的多功能工具，用于揭示一线抗癌药物顺铂在癌细胞群中的摄取多样性。一个感兴趣的研究人员提供了教程，以帮助适应这种尖端的方法和知识，以可靠的数据处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Differentiation of cisplatin uptake amid the population of cancer cells – how to 'crack this nut' using single-cell ICP-MS?

A versatile tool to unravel the uptake diversity of a front-line anticancer drug, cisplatin, within a cancer cell population is proposed herein based on single-cell inductively coupled plasma mass spectrometry. An interested researcher is provided with the tutorial to help adapt such cutting-edge methodology and know-how to reliable data processing.

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