{"title":"特发性肠系膜静脉硬化1例：相关血管钙化的发病机制探讨","authors":"Kimitoshi Kubo MD, PhD, Noriko Kimura MD, PhD","doi":"10.1002/jgf2.70025","DOIUrl":null,"url":null,"abstract":"<p>A 75-year-old woman had been taking a geniposide-containing herbal medicine for 7 years and was admitted to our hospital for nausea, abdominal pain, and distention. CT revealed colonic wall thickening, whereas CS revealed a dark-purple edematous mucosa. Furthermore, biopsy specimens revealed small vein hyalinization. Thus, she was diagnosed with idiopathic mesenteric phlebosclerosis (IMP) and underwent surgery. von Kossa staining revealed granules in the mucosal, submucosal, muscular, and subserosal layers, with mesenteric veins demonstrating calcium deposition. Taken together, calcium ion deposition was likely to have accounted for vascular wall calcification in IMP. The patient's course was uneventful for 3 months after surgery.</p>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":"26 5","pages":"475-478"},"PeriodicalIF":2.3000,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70025","citationCount":"0","resultStr":"{\"title\":\"A case of idiopathic mesenteric phlebosclerosis: Insight into pathogenesis of associated vascular calcification\",\"authors\":\"Kimitoshi Kubo MD, PhD, Noriko Kimura MD, PhD\",\"doi\":\"10.1002/jgf2.70025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A 75-year-old woman had been taking a geniposide-containing herbal medicine for 7 years and was admitted to our hospital for nausea, abdominal pain, and distention. CT revealed colonic wall thickening, whereas CS revealed a dark-purple edematous mucosa. Furthermore, biopsy specimens revealed small vein hyalinization. Thus, she was diagnosed with idiopathic mesenteric phlebosclerosis (IMP) and underwent surgery. von Kossa staining revealed granules in the mucosal, submucosal, muscular, and subserosal layers, with mesenteric veins demonstrating calcium deposition. Taken together, calcium ion deposition was likely to have accounted for vascular wall calcification in IMP. The patient's course was uneventful for 3 months after surgery.</p>\",\"PeriodicalId\":51861,\"journal\":{\"name\":\"Journal of General and Family Medicine\",\"volume\":\"26 5\",\"pages\":\"475-478\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-04-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.70025\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of General and Family Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of General and Family Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.70025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A case of idiopathic mesenteric phlebosclerosis: Insight into pathogenesis of associated vascular calcification
A 75-year-old woman had been taking a geniposide-containing herbal medicine for 7 years and was admitted to our hospital for nausea, abdominal pain, and distention. CT revealed colonic wall thickening, whereas CS revealed a dark-purple edematous mucosa. Furthermore, biopsy specimens revealed small vein hyalinization. Thus, she was diagnosed with idiopathic mesenteric phlebosclerosis (IMP) and underwent surgery. von Kossa staining revealed granules in the mucosal, submucosal, muscular, and subserosal layers, with mesenteric veins demonstrating calcium deposition. Taken together, calcium ion deposition was likely to have accounted for vascular wall calcification in IMP. The patient's course was uneventful for 3 months after surgery.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
