Mahdi A. Mohammed, Waleed K. Abdulkadhim, Kareem. H. Jawad, Salim Albukhaty, Majid S. Jabir, Suresh Ghotekar, Ayman A. Swelum
{"title":"磁增强ZnFe2O4纳米复合材料：一种有前途的抗菌和抗氧化策略","authors":"Mahdi A. Mohammed, Waleed K. Abdulkadhim, Kareem. H. Jawad, Salim Albukhaty, Majid S. Jabir, Suresh Ghotekar, Ayman A. Swelum","doi":"10.1007/s10971-025-06870-x","DOIUrl":null,"url":null,"abstract":"<div><p>The present study aimed to synthesize zinc ferrite nanoparticles (ZnFe<sub>2</sub>O<sub>4</sub> NPs) using the sol-gel method and evaluate their antibacterial properties against <i>Escherichia coli</i> (<i>E. coli</i>) and <i>Staphylococcus aureus</i> (<i>S. aureus</i>), along with an assessment of their antioxidant activity. Characterization, including X-ray diffraction (XRD) analysis, confirmed that the nanoparticles exhibited a face-centered cubic (FCC) crystalline structure. Transmission electron microscopy (TEM) revealed that the nanoparticles were spherical in shape, with an estimated size ranging from approximately (~30–60 nm). The magnetic properties were investigated using a vibrating sample magnetometer (VSM), while Fourier-transform infrared spectroscopy (FTIR) identified the functional groups present. Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited sustained antioxidant activity as measured by the DPPH assay. These combined antioxidant and AMF-enhanced antibacterial properties suggest promising pharmacological and biomedical applications for ZnFe<sub>2</sub>O<sub>4</sub> NPs, particularly in the development of magnetically responsive therapeutic agents. Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited sustained antioxidant activity as measured by the DPPH assay. 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Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited sustained antioxidant activity as measured by the DPPH assay. These combined antioxidant and AMF-enhanced antibacterial properties suggest promising pharmacological and biomedical applications for ZnFe<sub>2</sub>O<sub>4</sub> NPs, particularly in the development of magnetically responsive therapeutic agents. Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe<sub>2</sub>O<sub>4</sub> NPs exhibited sustained antioxidant activity as measured by the DPPH assay. 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Magnetically enhanced ZnFe2O4 nanocomposite: a promising antibacterial, and antioxidant strategies
The present study aimed to synthesize zinc ferrite nanoparticles (ZnFe2O4 NPs) using the sol-gel method and evaluate their antibacterial properties against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), along with an assessment of their antioxidant activity. Characterization, including X-ray diffraction (XRD) analysis, confirmed that the nanoparticles exhibited a face-centered cubic (FCC) crystalline structure. Transmission electron microscopy (TEM) revealed that the nanoparticles were spherical in shape, with an estimated size ranging from approximately (~30–60 nm). The magnetic properties were investigated using a vibrating sample magnetometer (VSM), while Fourier-transform infrared spectroscopy (FTIR) identified the functional groups present. Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe2O4 nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe2O4 NPs exhibited sustained antioxidant activity as measured by the DPPH assay. These combined antioxidant and AMF-enhanced antibacterial properties suggest promising pharmacological and biomedical applications for ZnFe2O4 NPs, particularly in the development of magnetically responsive therapeutic agents. Notably, this study presents a novel approach by demonstrating, for the first time, the enhanced antibacterial efficacy of ZnFe2O4 nanoparticles under an alternating magnetic field (AMF), highlighting their unique DNA-mediated mechanism of action. Furthermore, the ZnFe2O4 NPs exhibited sustained antioxidant activity as measured by the DPPH assay. These combined antioxidant and AMF-enhanced antibacterial properties suggest promising pharmacological and biomedical applications for ZnFe2O4 NPs, particularly in the development of magnetically responsive therapeutic agents.
期刊介绍：
The primary objective of the Journal of Sol-Gel Science and Technology (JSST), the official journal of the International Sol-Gel Society, is to provide an international forum for the dissemination of scientific, technological, and general knowledge about materials processed by chemical nanotechnologies known as the "sol-gel" process. The materials of interest include gels, gel-derived glasses, ceramics in form of nano- and micro-powders, bulk, fibres, thin films and coatings as well as more recent materials such as hybrid organic-inorganic materials and composites. Such materials exhibit a wide range of optical, electronic, magnetic, chemical, environmental, and biomedical properties and functionalities. Methods for producing sol-gel-derived materials and the industrial uses of these materials are also of great interest.
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