Synergistic nanotherapy enhances tumor and lymph node immunity

Adenosine is a key regulator of the immunosuppressive tumor microenvironment. In the August issue of Cell Biomaterials, Chen et al. introduce a synergistic tumor immunotherapy: magnetothermal immunotherapy. Using external magnetic control, this approach enhances immune activation by promoting ATP release while preventing its conversion to immunosuppressive adenosine. This synergistic nanotherapy offers a promising new strategy for cancer immunotherapy.