Cyril Meyer, Victor Hanss, Etienne Baudrier, Benoît Naegel, Patrick Schultz
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DeepSCEM: A User-Friendly Solution for Deep Learning-Based Image Segmentation in Cellular Electron Microscopy
Deep learning methods using convolutional neural networks are very effective for automatic image segmentation tasks with no exception for cellular electron micrographs. However, the lack of dedicated easy-to-use tools largely reduces the widespread use of these techniques. Here we present DeepSCEM, a straightforward tool for fast and efficient segmentation of cellular electron microscopy images using deep learning with a special focus on efficient and user-friendly generation and training of models for organelle segmentation.
期刊介绍:
The journal publishes original research articles and reviews on all aspects of cellular, molecular and structural biology, developmental biology, cell physiology and evolution. It will publish articles or reviews contributing to the understanding of the elementary biochemical and biophysical principles of live matter organization from the molecular, cellular and tissues scales and organisms.
This includes contributions directed towards understanding biochemical and biophysical mechanisms, structure-function relationships with respect to basic cell and tissue functions, development, development/evolution relationship, morphogenesis, stem cell biology, cell biology of disease, plant cell biology, as well as contributions directed toward understanding integrated processes at the organelles, cell and tissue levels. Contributions using approaches such as high resolution imaging, live imaging, quantitative cell biology and integrated biology; as well as those using innovative genetic and epigenetic technologies, ex-vivo tissue engineering, cellular, tissue and integrated functional analysis, and quantitative biology and modeling to demonstrate original biological principles are encouraged.