Nazar Khalaf Mahan, Mohammed Faraj Al-Marjani, Ganesan Krishnan, Mohammed A. Salman
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引用次数: 0
摘要
嗜酸乳杆菌(LB)可以生产高纯度纳米颗粒;它是一种自上而下的生物学方法,基于将金属离子体前体分解成金属原子的原理;本文采用该生物合成方法合成了CoCrCuFeNi高熵合金。采用XRD、SEM、FTIR等分析手段对合成的纳米颗粒进行了表征。随后,对从尿路感染中分离出来的革兰氏阳性细菌金黄色葡萄球菌(S. aureus)和革兰氏阴性细菌大肠杆菌(E. coli)进行了抗菌和抗生物膜活性测试。结果表明,通过LB制备的CoCrCuFeNi HEA NPs与CoCrCuFeNi HEA NPs + LB上清液对大肠杆菌和金黄色葡萄球菌的抑菌区分别为35 mm和25 mm。另一方面,CoCrCuFeNi HEA NPs + LB在导管上对大肠杆菌的抗菌膜有效性超过45%。
Characterization and Antibacterial Properties of CoCrCuFeNi High-Entropy Alloy Nanoparticles Synthesized by Lactobacillus acidophilus
Lactobacillus acidophilus (LB) can produce high-purity nanoparticles; it is a top-down biological method based on the principle of dividing metal ion bulk precursors into metal atoms; this biosynthesis method was used in this work to synthesize CoCrCuFeNi high-entropy alloy. The characteristics of the synthesized nanoparticles were examined using XRD, SEM, and FTIR analysis. Subsequently, their antibacterial and antibiofilm activities were tested against a Gram-positive bacteria Staphylococcus aureus (S. aureus) and a Gram-negative bacteria Escherichia coli (E. coli) that were isolated from the urinary tract infection. The results indicated that CoCrCuFeNi HEA NPs produced via the LB, along with CoCrCuFeNi HEA NPs + LB supernatant, displayed antibacterial inhibition zones measuring 35 mm against E. coli and 25 mm against S. aureus. On the other hand, the antibiofilm effectiveness of the CoCrCuFeNi HEA NPs + LB on a catheter was determined to surpass 45% against E. coli.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.