{"title":"复发难治性多发性骨髓瘤继发髓外浆细胞瘤的多灶性结肠肿块一例报告及文献复习","authors":"Sirisha Gaddipati, Sunny Sandhu, Eric F. Martin","doi":"10.1002/jgh3.70239","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Multiple myeloma (MM) is a common plasma cell malignancy; however, extramedullary multiple myeloma (EMM) is an aggressive phenotype in which malignant plasma cells proliferate outside of the bone marrow.</p>\n </section>\n \n <section>\n \n <h3> Aims</h3>\n \n <p>Extramedullary plasmacytomas (EMP) are uncommon and gastrointestinal involvement is exceedingly rare.</p>\n </section>\n \n <section>\n \n <h3> Case Presentation</h3>\n \n <p>Here, we present a case of multifocal secondary colonic EMP in a patient with relapsed refractory multiple myeloma (RRMM) and review literature demonstrating other cases of secondary colonic EMP.</p>\n </section>\n </div>","PeriodicalId":45861,"journal":{"name":"JGH Open","volume":"9 9","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgh3.70239","citationCount":"0","resultStr":"{\"title\":\"Multifocal Colonic Masses as a Presentation of Secondary Extramedullary Plasmacytoma in Relapsing-Refractory Multiple Myeloma: A Case Report and Review of Literature\",\"authors\":\"Sirisha Gaddipati, Sunny Sandhu, Eric F. Martin\",\"doi\":\"10.1002/jgh3.70239\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Multiple myeloma (MM) is a common plasma cell malignancy; however, extramedullary multiple myeloma (EMM) is an aggressive phenotype in which malignant plasma cells proliferate outside of the bone marrow.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Aims</h3>\\n \\n <p>Extramedullary plasmacytomas (EMP) are uncommon and gastrointestinal involvement is exceedingly rare.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Case Presentation</h3>\\n \\n <p>Here, we present a case of multifocal secondary colonic EMP in a patient with relapsed refractory multiple myeloma (RRMM) and review literature demonstrating other cases of secondary colonic EMP.</p>\\n </section>\\n </div>\",\"PeriodicalId\":45861,\"journal\":{\"name\":\"JGH Open\",\"volume\":\"9 9\",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgh3.70239\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JGH Open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jgh3.70239\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JGH Open","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jgh3.70239","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Multifocal Colonic Masses as a Presentation of Secondary Extramedullary Plasmacytoma in Relapsing-Refractory Multiple Myeloma: A Case Report and Review of Literature
Background
Multiple myeloma (MM) is a common plasma cell malignancy; however, extramedullary multiple myeloma (EMM) is an aggressive phenotype in which malignant plasma cells proliferate outside of the bone marrow.
Aims
Extramedullary plasmacytomas (EMP) are uncommon and gastrointestinal involvement is exceedingly rare.
Case Presentation
Here, we present a case of multifocal secondary colonic EMP in a patient with relapsed refractory multiple myeloma (RRMM) and review literature demonstrating other cases of secondary colonic EMP.
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