Francesco Pallotti , Alessandra Buonacquisto , Gaia Cicolani , Anna Chiara Conflitti , Francesco Lombardo , Donatella Paoli
{"title":"近几十年来男性生育障碍发病率的演变","authors":"Francesco Pallotti , Alessandra Buonacquisto , Gaia Cicolani , Anna Chiara Conflitti , Francesco Lombardo , Donatella Paoli","doi":"10.1016/j.mam.2025.101398","DOIUrl":null,"url":null,"abstract":"<div><div>Male reproductive health evaluation involves andrological and sexological clinical problems but, on a wider scale, it also involves other public health issues, including lifestyle and metabolic factors. These factors, especially if combined with pre-existing andrological diseases, have been found to be significantly associated with semen parameters impairment and, thus, male infertility. A hypothesized trend of decline of male fertility has been debated in the last years and this aspect is strictly intertwined with the evolution of the incidence of male fertility disorders over the last decades. It should be stressed that all these factors harbour relevant repercussions for both individual reproductive health as well as broader socio-economic and demographic issues. Thus, the aim of this review is to perform a short and critical overview of the andrological issues affecting the reproductive outcomes of the infertile male as well as provide a comprehensive and critical overview of the male fertility decline issue.</div></div>","PeriodicalId":49798,"journal":{"name":"Molecular Aspects of Medicine","volume":"105 ","pages":"Article 101398"},"PeriodicalIF":10.3000,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evolution of the incidence of male fertility disorders over the last decades\",\"authors\":\"Francesco Pallotti , Alessandra Buonacquisto , Gaia Cicolani , Anna Chiara Conflitti , Francesco Lombardo , Donatella Paoli\",\"doi\":\"10.1016/j.mam.2025.101398\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Male reproductive health evaluation involves andrological and sexological clinical problems but, on a wider scale, it also involves other public health issues, including lifestyle and metabolic factors. These factors, especially if combined with pre-existing andrological diseases, have been found to be significantly associated with semen parameters impairment and, thus, male infertility. A hypothesized trend of decline of male fertility has been debated in the last years and this aspect is strictly intertwined with the evolution of the incidence of male fertility disorders over the last decades. It should be stressed that all these factors harbour relevant repercussions for both individual reproductive health as well as broader socio-economic and demographic issues. Thus, the aim of this review is to perform a short and critical overview of the andrological issues affecting the reproductive outcomes of the infertile male as well as provide a comprehensive and critical overview of the male fertility decline issue.</div></div>\",\"PeriodicalId\":49798,\"journal\":{\"name\":\"Molecular Aspects of Medicine\",\"volume\":\"105 \",\"pages\":\"Article 101398\"},\"PeriodicalIF\":10.3000,\"publicationDate\":\"2025-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Molecular Aspects of Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0098299725000627\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Aspects of Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0098299725000627","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Evolution of the incidence of male fertility disorders over the last decades
Male reproductive health evaluation involves andrological and sexological clinical problems but, on a wider scale, it also involves other public health issues, including lifestyle and metabolic factors. These factors, especially if combined with pre-existing andrological diseases, have been found to be significantly associated with semen parameters impairment and, thus, male infertility. A hypothesized trend of decline of male fertility has been debated in the last years and this aspect is strictly intertwined with the evolution of the incidence of male fertility disorders over the last decades. It should be stressed that all these factors harbour relevant repercussions for both individual reproductive health as well as broader socio-economic and demographic issues. Thus, the aim of this review is to perform a short and critical overview of the andrological issues affecting the reproductive outcomes of the infertile male as well as provide a comprehensive and critical overview of the male fertility decline issue.
期刊介绍:
Molecular Aspects of Medicine is a review journal that serves as an official publication of the International Union of Biochemistry and Molecular Biology. It caters to physicians and biomedical scientists and aims to bridge the gap between these two fields. The journal encourages practicing clinical scientists to contribute by providing extended reviews on the molecular aspects of a specific medical field. These articles are written in a way that appeals to both doctors who may struggle with basic science and basic scientists who may have limited awareness of clinical practice issues. The journal covers a wide range of medical topics to showcase the molecular insights gained from basic science and highlight the challenging problems that medicine presents to the scientific community.