Nick Townsend , Adam Timmis , Andrejs Erglis , Davor Miličić , Pasquale Perrone-Filardi , Franz Weidinger , Tomasz Guzik , Chris P. Gale
{"title":"老年人心血管疾病预防、治疗和管理的挑战","authors":"Nick Townsend , Adam Timmis , Andrejs Erglis , Davor Miličić , Pasquale Perrone-Filardi , Franz Weidinger , Tomasz Guzik , Chris P. Gale","doi":"10.1016/j.lanepe.2025.101372","DOIUrl":null,"url":null,"abstract":"<div><div>The ageing population in Europe is contributing to a growing proportion of older people affected by cardiovascular disease (CVD). Older adults account for most of the CVD burden and face unique challenges, complicated by age-related physiological changes and comorbidities. Older patients are underrepresented in clinical trials, leading to scientific and clinical equipoise, and inequities in care. Managing CVD in this age group is complex. Despite the availability of guideline-directed therapies, older adults often do not receive optimal treatment due to the complexity of their conditions and are at higher risk of complications. Strategies for the treatment and management of CVD in older individuals should be driven by patient centred outcomes relating to functional capacity and quality of life. Social and economic factors, such as financial limitations and isolation, further exacerbate age-related CVD inequalities and highlight the need for a holistic approach to care. To address this challenge, The Lancet Regional Health–Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among older adults and propose recommendations to address these disparities. This Series paper aims to explore inequalities in, and the escalating burden of, CVD for older adults, with a focus on treatment, prevention, and strategies to support their physical and mental well-being.</div></div>","PeriodicalId":53223,"journal":{"name":"Lancet Regional Health-Europe","volume":"56 ","pages":"Article 101372"},"PeriodicalIF":13.0000,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Challenges in the prevention, treatment and management of cardiovascular disease among older adults\",\"authors\":\"Nick Townsend , Adam Timmis , Andrejs Erglis , Davor Miličić , Pasquale Perrone-Filardi , Franz Weidinger , Tomasz Guzik , Chris P. Gale\",\"doi\":\"10.1016/j.lanepe.2025.101372\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The ageing population in Europe is contributing to a growing proportion of older people affected by cardiovascular disease (CVD). Older adults account for most of the CVD burden and face unique challenges, complicated by age-related physiological changes and comorbidities. Older patients are underrepresented in clinical trials, leading to scientific and clinical equipoise, and inequities in care. Managing CVD in this age group is complex. Despite the availability of guideline-directed therapies, older adults often do not receive optimal treatment due to the complexity of their conditions and are at higher risk of complications. Strategies for the treatment and management of CVD in older individuals should be driven by patient centred outcomes relating to functional capacity and quality of life. Social and economic factors, such as financial limitations and isolation, further exacerbate age-related CVD inequalities and highlight the need for a holistic approach to care. To address this challenge, The Lancet Regional Health–Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among older adults and propose recommendations to address these disparities. This Series paper aims to explore inequalities in, and the escalating burden of, CVD for older adults, with a focus on treatment, prevention, and strategies to support their physical and mental well-being.</div></div>\",\"PeriodicalId\":53223,\"journal\":{\"name\":\"Lancet Regional Health-Europe\",\"volume\":\"56 \",\"pages\":\"Article 101372\"},\"PeriodicalIF\":13.0000,\"publicationDate\":\"2025-08-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lancet Regional Health-Europe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666776225001644\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lancet Regional Health-Europe","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666776225001644","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
Challenges in the prevention, treatment and management of cardiovascular disease among older adults
The ageing population in Europe is contributing to a growing proportion of older people affected by cardiovascular disease (CVD). Older adults account for most of the CVD burden and face unique challenges, complicated by age-related physiological changes and comorbidities. Older patients are underrepresented in clinical trials, leading to scientific and clinical equipoise, and inequities in care. Managing CVD in this age group is complex. Despite the availability of guideline-directed therapies, older adults often do not receive optimal treatment due to the complexity of their conditions and are at higher risk of complications. Strategies for the treatment and management of CVD in older individuals should be driven by patient centred outcomes relating to functional capacity and quality of life. Social and economic factors, such as financial limitations and isolation, further exacerbate age-related CVD inequalities and highlight the need for a holistic approach to care. To address this challenge, The Lancet Regional Health–Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among older adults and propose recommendations to address these disparities. This Series paper aims to explore inequalities in, and the escalating burden of, CVD for older adults, with a focus on treatment, prevention, and strategies to support their physical and mental well-being.
期刊介绍:
The Lancet Regional Health – Europe, a gold open access journal, is part of The Lancet's global effort to promote healthcare quality and accessibility worldwide. It focuses on advancing clinical practice and health policy in the European region to enhance health outcomes. The journal publishes high-quality original research advocating changes in clinical practice and health policy. It also includes reviews, commentaries, and opinion pieces on regional health topics, such as infection and disease prevention, healthy aging, and reducing health disparities.